[HTML][HTML] Conservation of biodiversity in the genomics era

MA Supple, B Shapiro - Genome biology, 2018 - Springer
“Conservation genomics” encompasses the idea that genome-scale data will improve the
capacity of resource managers to protect species. Although genetic approaches have long …

Genomic variation across landscapes: insights and applications

JG Bragg, MA Supple, RL Andrew… - New Phytologist, 2015 - Wiley Online Library
The distribution of genomic variation across landscapes can provide insights into the complex
interactions between the environment and the genome that influence the distribution of …

Evolutionary constraint and innovation across hundreds of placental mammals

…, SK Reilly, DE Schäffer, C Steiner, MA Supple… - Science, 2023 - science.org
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

The gene cortex controls mimicry and crypsis in butterflies and moths

NJ Nadeau, C Pardo-Diaz, A Whibley, MA Supple… - Nature, 2016 - nature.com
The wing patterns of butterflies and moths (Lepidoptera) are diverse and striking examples
of evolutionary diversification by natural selection 1 , 2 . Lepidopteran wing colour patterns …

Complex modular architecture around a simple toolkit of wing pattern genes

…, SH Martin, CF Arias, MA Supple… - Nature ecology & …, 2017 - nature.com
Identifying the genomic changes that control morphological variation and understanding how
they generate diversity is a major goal of evolutionary biology. In Heliconius butterflies, a …

Mammalian evolution of human cis-regulatory elements and transcription factor binding sites

…, KAM Sullivan, PF Sullivan, E Sundström, MA Supple… - Science, 2023 - science.org
Understanding the regulatory landscape of the human genome is a long-standing objective
of modern biology. Using the reference-free alignment across 241 mammalian genomes …

The contribution of historical processes to contemporary extinction risk in placental mammals

AP Wilder, MA Supple, A Subramanian, A Mudide… - Science, 2023 - science.org
Species persistence can be influenced by the amount, type, and distribution of diversity
across the genome, suggesting a potential relationship between historical demography and …

[HTML][HTML] Puma genomes from North and South America provide insights into the genomic consequences of inbreeding

NF Saremi, MA Supple, A Byrne, JA Cahill… - Nature …, 2019 - nature.com
Pumas are the most widely distributed felid in the Western Hemisphere. Increasingly,
however, human persecution and habitat loss are isolating puma populations. To explore the …

Glacial ice supports a distinct and undocumented polar bear subpopulation persisting in late 21st-century sea-ice conditions

KL Laidre, MA Supple, EW Born, EV Regehr, Ø Wiig… - Science, 2022 - science.org
Polar bears are susceptible to climate warming because of their dependence on sea ice,
which is declining rapidly. We present the first evidence for a genetically distinct and …

Genomic architecture of adaptive color pattern divergence and convergence in Heliconius butterflies

MA Supple, HM Hines, KK Dasmahapatra… - Genome …, 2013 - genome.cshlp.org
Identifying the genetic changes driving adaptive variation in natural populations is key to
understanding the origins of biodiversity. The mosaic of mimetic wing patterns in Heliconius …