Many organs are composed of epithelial tubes that transport vital fluids. Such tubular organs
develop in many different ways and generate tubes of widely varying sizes and structures, …

… Manning and MA Krasnow, in The Development of Drosophila melanogaster, M. Bate and
A… Cardoso and members of the Krasnow lab for comments on the manuscript. MAK is an …

Since Joseph Priestley's demonstration in 1774 of the deleterious effects of a burning
candle on a mouse in a bell jar, we have known that oxygen is essential for animal life. Only …

Single-cell technologies have transformed our understanding of human tissues. Yet, studies
typically capture only a limited number of donors and disagree on cell type definitions. …

Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …

… for help and discussions regarding bioinformatic pipelines and statistical analysis, SI
Gonzalez for help with immunofluorescence, and JG Camp and members of the Krasnow …

Although single-cell RNA sequencing studies have begun to provide compendia of cell
expression profiles 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 – 9 , it has been difficult to systematically identify and …

Molecular genetic studies of Drosophila melanogaster have led to profound advances in
understanding the regulation of development. Here we report gene expression patterns for …

… Chapman, and members of the Krasnow laboratory for discussions and comments on the
manuscript; and Maria Petersen for help preparing figures and the manuscript. …

Antagonists of several growth factor signaling pathways play important roles in developmental
patterning by limiting the range of the cognate inducer. Here, we describe an antagonist …