In embryonic stem (ES) cells and in early mouse embryos, the transcription factor Oct4 is an
essential regulator of pluripotency. Oct4 transcriptional targets have been described in ES …

We here identify and characterize an extracellular modulator of Hedgehog signaling in
Drosophila, Shifted. Shifted is required for high levels of long-range signaling in the developing …

The reprogramming factors OCT4, SOX2, KLF4, and MYC (OSKM) can reactivate the
pluripotency network in terminally differentiated cells, but also regulate expression of non-…

Pioneer transcription factors (TFs), such as OCT4 and SOX2, play crucial roles in pluripotency
regulation. However, the master TF-governed pluripotency regulatory circuitry was largely …

An unintended consequence of fish stocking is genetic homogenization from interbreeding
between indigenous populations and genetically distinct hatchery strains. Lake trout …

The inner cell mass ( ICM ) of the mammalian blastocyst contains pluripotent epiblast ( EPI )
and differentiating primitive endoderm ( PE ) cells, intermingled like salt and pepper. In …

… Grandma Rose Halbisen (Mettler) somewhat inadvertently introduced me to probability …
Halbisen gave me his interest in the mechanical aspects of the world. I am grateful to him for …

Learning to write a scientific manuscript is one of the most important and rewarding scientific
training experiences, yet most young scientists only embark on this experience relatively …

During development, progenitors of embryonic stem (ES) and extraembryonic endoderm
stem (XEN) cells are concomitantly specified within the inner cell mass (ICM) of the mouse …

… Furthermore, I would like to thank my spouse Stephanie Halbeisen, not only for proofreading
… The question is now, can we say anything about r and c if we assume neither CH nor MA? …