User profiles for M. A. Bakowski
Malina A. BakowskiPrincipal Investigator, California Institute for Biomedical Research Verified email at calibr.org Cited by 3653 |
Salmonella‐Containing Vacuoles: Directing Traffic and Nesting to Grow
MA Bakowski, V Braun, JH Brumell - Traffic, 2008 - Wiley Online Library
Salmonella enterica serovar Typhimurium (S. typhimurium) is a gram‐negative facultative
intracellular pathogen that can infect a broad range of mammalian hosts. Following invasion of …
intracellular pathogen that can infect a broad range of mammalian hosts. Following invasion of …
Alternative splicing of conserved exons is frequently species-specific in human and mouse
In this article, we provide evidence that a frequent source of diversity between mammalian
transcripts occurs as a consequence of species-specific alternative splicing (AS) of conserved …
transcripts occurs as a consequence of species-specific alternative splicing (AS) of conserved …
[HTML][HTML] Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
…, D Arenson, L Aschenbrenner, MA Bakowski… - Nature …, 2021 - nature.com
COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …
[HTML][HTML] Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole
CL Birmingham, AC Smith, MA Bakowski… - Journal of Biological …, 2006 - ASBMB
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative intracellular
pathogen that causes disease in a variety of hosts. S. Typhimurium actively invade host cells and …
pathogen that causes disease in a variety of hosts. S. Typhimurium actively invade host cells and …
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth
…, MA Bakowski, J Goldberg, AT Ma… - Genome …, 2012 - genome.cshlp.org
Microsporidia comprise a large phylum of obligate intracellular eukaryotes that are fungal-related
parasites responsible for widespread disease, and here we address questions about …
parasites responsible for widespread disease, and here we address questions about …
[HTML][HTML] The functional landscape of mouse gene expression
W Zhang, QD Morris, R Chang, O Shai, MA Bakowski… - Journal of biology, 2004 - Springer
Background Large-scale quantitative analysis of transcriptional co-expression has been
used to dissect regulatory networks and to predict the functions of new genes discovered by …
used to dissect regulatory networks and to predict the functions of new genes discovered by …
[HTML][HTML] Drug repurposing screens identify chemical entities for the development of COVID-19 interventions
MA Bakowski, N Beutler, KC Wolff… - Nature …, 2021 - nature.com
The ongoing pandemic caused by the novel severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), necessitates strategies to identify prophylactic and therapeutic drug …
2 (SARS-CoV-2), necessitates strategies to identify prophylactic and therapeutic drug …
Discovery of a novel inhibitor of coronavirus 3CL protease for the potential treatment of COVID-19
…, D Arenson, L Aschenbrenner, MA Bakowski… - BioRxiv, 2020 - biorxiv.org
COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease
is a virally encoded protein that is essential to the viral life cycle across a broad spectrum of …
is a virally encoded protein that is essential to the viral life cycle across a broad spectrum of …
[HTML][HTML] Ubiquitin-Mediated Response to Microsporidia and Virus Infection in C. elegans
Microsporidia comprise a phylum of over 1400 species of obligate intracellular pathogens
that can infect almost all animals, but little is known about the host response to these parasites…
that can infect almost all animals, but little is known about the host response to these parasites…
[PDF][PDF] The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole
Shifts in electrostatic surface charge of membranes have recently been highlighted as a
significant factor contributing to protein targeting to the plasma membrane and nascent …
significant factor contributing to protein targeting to the plasma membrane and nascent …