User profiles for L. de Oliveira Martins

Leonardo de Oliveira Martins

Head of Phylogenomics, Quadram Institute Bioscience
Verified email at quadram.ac.uk
Cited by 5213

SimPhy : Phylogenomic Simulation of Gene, Locus, and Species Trees

D Mallo, L de Oliveira Martins, D Posada - Systematic biology, 2016 - academic.oup.com
We present a fast and flexible software package—SimPhy—for the simulation of multiple gene
families evolving under incomplete lineage sorting, gene duplication and loss, horizontal …

[PDF][PDF] The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

…, D de Angelis, E De Lacy, L de Oliveira Martins… - Iscience, 2021 - cell.com
We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating
global sequence data. Several variants within nucleocapsid and ORF3a epitopes have …

[PDF][PDF] Detection of masses in digital mammograms using K-means and support vector machine

L de Oliveira Martins, GB Junior, AC Silva… - … Electronic Letters on …, 2009 - elcvia.cvc.uab.cat
… Leonardo de Oliveira Martins et al. / Electronic Letters on Computer Vision and Image
Analysis 8(2):39-50, 2009 … Leonardo de Oliveira Martins et al. / Electronic Letters on …

Nanoneedle-mediated stimulation of cell mechanotransduction machinery

…, L de Oliveira Martins, D Keller… - ACS …, 2019 - ACS Publications
… Leonardo de Oliveira Martins Leonardo de Oliveira Martins … (D) Western blot shows
downregulation of vinculin protein expression on nN (HUVEC: N = 2, hMSC: N = 3, mean ± SD). (E) …

[HTML][HTML] CoronaHiT: high-throughput sequencing of SARS-CoV-2 genomes

…, T Le-Viet, GL Kay, S Rudder, L de Oliveira Martins… - Genome medicine, 2021 - Springer
We present CoronaHiT, a platform and throughput flexible method for sequencing SARS-CoV-2
genomes (≤ 96 on MinION or > 96 on Illumina NextSeq) depending on changing …

[HTML][HTML] Dynamics of competing SARS-CoV-2 variants during the Omicron epidemic in England

O Eales, L de Oliveira Martins, AJ Page, H Wang… - Nature …, 2022 - nature.com
The SARS-CoV-2 pandemic has been characterised by the regular emergence of genomic
variants. With natural and vaccine-induced population immunity at high levels, evolutionary …

Large-scale sequencing of SARS-CoV-2 genomes from one region allows detailed epidemiology and enables local outbreak management

…, GL Kay, L de Oliveira Martins… - Microbial …, 2021 - microbiologyresearch.org
The COVID-19 pandemic has spread rapidly throughout the world. In the UK, the initial peak
was in April 2020; in the county of Norfolk (UK) and surrounding areas, which has a stable, …

The consequences for stream water quality of long-term changes in landscape patterns: Implications for land use management and policies

ACP Fernandes, LM de Oliveira Martins, FAL Pacheco… - Land Use Policy, 2021 - Elsevier
… Author links open overlay panel António Carlos Pinheiro Fernandes a , Lisa Maria de
Oliveira Martins a , Fernando António Leal Pacheco b , Luís Filipe Sanches Fernandes a …

[HTML][HTML] SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY. 4.2

O Eales, AJ Page, L de Oliveira Martins, H Wang… - BMC infectious …, 2022 - Springer
Background Since the emergence of SARS-CoV-2, evolutionary pressure has driven large
increases in the transmissibility of the virus. However, with increasing levels of immunity …

[HTML][HTML] Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected …

T Mashe, FT Takawira, L de Oliveira Martins… - The Lancet Global …, 2021 - thelancet.com
Background Advances in SARS-CoV-2 sequencing have enabled identification of new
variants, tracking of its evolution, and monitoring of its spread. We aimed to use whole genome …