Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA …
…, A Haudry, L Waidele… - Molecular Biology …, 2020 - academic.oup.com
Genetic variation is the fuel of evolution, with standing genetic variation especially important
for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of …
for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of …
Common structuring principles of the Drosophila melanogaster microbiome on a continental scale and between host and substrate
Y Wang, M Kapun, L Waidele, S Kuenzel… - Environmental …, 2020 - Wiley Online Library
The relative importance of host control, environmental effects and stochasticity in the
assemblage of host‐associated microbiomes is being debated. We analysed the microbiome …
assemblage of host‐associated microbiomes is being debated. We analysed the microbiome …
[HTML][HTML] Differential ecological specificity of protist and bacterial microbiomes across a set of termite species
L Waidele, J Korb, CR Voolstra, S Künzel… - Frontiers in …, 2017 - frontiersin.org
The gut microbiome of lower termites comprises protists and bacteria that help these insects
to digest cellulose and to thrive on wood. The composition of the termite gut microbiome …
to digest cellulose and to thrive on wood. The composition of the termite gut microbiome …
[HTML][HTML] Pharmacokinetics, pharmacodynamics and antiviral efficacy of the MEK inhibitor zapnometinib in animal models and in humans
J Koch-Heier, A Schönsiegel, LM Waidele… - Frontiers in …, 2022 - frontiersin.org
The mitogen-activated protein kinase (MEK) inhibitor zapnometinib is in development to
treat acute viral infections like COVID-19 and influenza. While the antiviral efficacy of …
treat acute viral infections like COVID-19 and influenza. While the antiviral efficacy of …
[HTML][HTML] Ecological specificity of the metagenome in a set of lower termite species supports contribution of the microbiome to adaptation of the host
Background Elucidating the interplay between hosts and their microbiomes in ecological
adaptation has become a central theme in evolutionary biology. A textbook example of …
adaptation has become a central theme in evolutionary biology. A textbook example of …
Genomic analysis of European Drosophila populations reveals longitudinal structure and continent-wide selection
Genetic variation is the fuel of evolution. However, analyzing evolutionary dynamics in
natural populations is challenging, sequencing of entire populations remains costly and …
natural populations is challenging, sequencing of entire populations remains costly and …
Genomic analysis of European Drosophila melanogaster populations on a dense spatial scale reveals longitudinal population structure and continent-wide selection
Genetic variation is the fuel of evolution. However, analyzing dynamics of evolutionary change
in natural populations is challenging, genome sequencing of entire populations remains …
in natural populations is challenging, genome sequencing of entire populations remains …
Continent-wide structure of bacterial microbiomes of European Drosophila melanogaster suggests host-control
Y Wang, M Kapun, L Waidele, S Kuenzel, A Bergland… - bioRxiv, 2019 - biorxiv.org
The relative importance of host-control, environmental effects, and stochasticity in the assemblage
of host-associated microbiomes has been much debated. With recent sampling efforts…
of host-associated microbiomes has been much debated. With recent sampling efforts…
Bacterial but not protist gut microbiota align with ecological specialization in a set of lower termite species
The role of microbes in adaptation of higher organisms to the environment is becoming
increasingly evident, but remains poorly understood. Protist and bacterial microbes facilitate that …
increasingly evident, but remains poorly understood. Protist and bacterial microbes facilitate that …
Investigation of surface effects of simple flux tubes using numerical simulations
M Waidele, M Roth - The Astrophysical Journal, 2020 - iopscience.iop.org
We use the SPARC code for MHD simulations with monolithic flux tubes of varying subsurface
topology. Our studies involve the interactions of waves caused by a single source with …
topology. Our studies involve the interactions of waves caused by a single source with …