… The authors thank all the members of the Dalla-Favera and Pasqualucci laboratories for
their contribution to the generation of data reported in this manuscript and apologize to those …

… The authors thank all the members of the Dalla-Favera and Pasqualucci laboratories for
their contribution to the generation of data reported in this manuscript, and apologize to those …

Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype with poor prognosis 1 ,
2 , 3 . We sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an …

Background Hairy-cell leukemia (HCL) is a well-defined clinicopathological entity whose
underlying genetic lesion is still obscure. Methods We searched for HCL-associated mutations …

Background Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent
nucleolar localization, regulates the ARF-p53 tumor-suppressor pathway. Translocations …

B-cell non-Hodgkin’s lymphoma comprises biologically and clinically distinct diseases the
pathogenesis of which is associated with genetic lesions affecting oncogenes and tumour-…

Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with recognized variability
in clinical outcome, genetic features, and cells of origin. To date, transcriptional profiling …

In past years, substantial insight regarding the pathogenesis of diffuse large B-cell lymphoma
has been obtained. Particularly, based on gene expression profile analysis, this disease …

Genomic instability promotes tumorigenesis and can occur through various mechanisms,
including defective segregation of chromosomes or inactivation of DNA mismatch repair 1 . …

… the identification of a few highly recurrent genetic lesions (Pasqualucci et al., 2011). This result
… L. Pasqualucci is on leave from the Institute of Hematology, University of Perugia Medical …