A cell membrane can be considered a liquid-phase plane in which lipids and proteins
theoretically are free to diffuse. Numerous reports, however, describe retarded diffusion of …

Rho guanosine triphosphatases (GTPases) are master regulators of cell signaling, but how
they are regulated depending on the cellular context is unclear. We found that the …

Membrane surface charge is critical for the transient, yet specific recruitment of proteins with
polybasic regions to certain organelles. In eukaryotes, the plasma membrane (PM) is the …

Cells maintain a constant dialog between the extracellular matrix and their plasma membrane
to fine tune signal transduction processes. We found that the receptor kinase FERONIA (…

Cardiolipin ( CL ) is the signature phospholipid of the mitochondrial inner membrane. In
animals and yeast (Saccharomyces cerevisiae), CL depletion affects the stability of respiratory …

The plant plasma membrane (PM) is an essential barrier between the cell and the external
environment, controlling signal perception and transmission. It consists of an asymmetrical …

Lipids have an established role as structural components of membranes or as signalling
molecules, but their role as molecular actors in protein secretion is less clear. The complex …

… To this end, we used the grapevine Vitis vinifera L. cultivar Gamay Teinturier (syn. Gamay
Freaux or Freaux Tintorier, VIVC #4382) cell suspension line as a model system to study the …

… Transformant colonies were inoculated into 5 ml of YEB medium (5 g/l beef extract, 1 g/l
yeast extract, 5 g/l sucrose and 0.5 g/l MgSO 4 ·7H 2 O) with 50 μg/ml spectinomycin and …

Doxorubicin (DXR) is a drug widely used in chemotherapy. Its mode of action is based on its
intercalation properties, involving the inhibition of topoisomerase II. However, few studies …