User profiles for L. Manco

Licinio Manco

University of Coimbra
Verified email at antrop.uc.pt
Cited by 1937

Current review of genetics of human obesity: from molecular mechanisms to an evolutionary perspective

…, E Stice, R Rodríguez-López, L Manco… - Molecular genetics and …, 2015 - Springer
It is well-known that obesity is a complex multifactorial and heterogeneous condition with an
important genetic component. Recently, major advances in obesity research emerged …

The contribution of genetics and environment to obesity

D Albuquerque, C Nóbrega, L Manco… - British medical …, 2017 - academic.oup.com
Background Obesity is a global health problem mainly attributed to lifestyle changes such
as diet, low physical activity or socioeconomics factors. However, several evidences …

[HTML][HTML] PET-derived radiomics and artificial intelligence in breast cancer: a systematic review

L Urso, L Manco, A Castello, L Evangelista… - International Journal of …, 2022 - mdpi.com
Breast cancer (BC) is a heterogeneous malignancy that still represents the second cause of
cancer-related death among women worldwide. Due to the heterogeneity of BC, the correct …

[HTML][HTML] The population genomics of archaeological transition in west Iberia: Investigation of ancient substructure using imputation and haplotype-based methods

…, R Ó'Maoldúin, R McLaughlin, NM Silva, L Manco… - PLoS …, 2017 - journals.plos.org
We analyse new genomic data (0.05–2.95x) from 14 ancient individuals from Portugal
distributed from the Middle Neolithic (4200–3500 BC) to the Middle Bronze Age (1740–1430 BC) …

Basic of machine learning and deep learning in imaging for medical physicists

L Manco, N Maffei, S Strolin, S Vichi, L Bottazzi… - Physica Medica, 2021 - Elsevier
The manuscript aims at providing an overview of the published algorithms/automation tool
for artificial intelligence applied to imaging for Healthcare. A PubMed search was performed …

[HTML][HTML] Association of FTO Polymorphisms with Obesity and Obesity-Related Outcomes in Portuguese Children

D Albuquerque, C Nóbrega, L Manco - PloS one, 2013 - journals.plos.org
Background Several studies have reported an association between single nucleotide
polymorphisms in the first intron of the FTO gene and body mass index (BMI) or obesity. However, …

DNA methylation age estimation in blood samples of living and deceased individuals using a multiplex SNaPshot assay

…, J Pereira, C Pinto, FC Real, E Cunha, L Manco - Forensic science …, 2020 - Elsevier
Many studies in the forensic field have reported that analysis of DNA methylation is the most
reliable method of predicting age. In a previous study, 5 CpG sites located in ELOVL2, FHL2…

[HTML][HTML] Association study of common polymorphisms in MSRA, TFAP2B, MC4R, NRXN3, PPARGC1A, TMEM18, SEC16B, HOXB5 and OLFM4 genes with obesity …

…, C Nóbrega, R Rodríguez-López, L Manco - Journal of human …, 2014 - nature.com
At least 52 genetic loci were associated with obesity-related traits. However, little is known
about the genetic basis of obesity among children. This study aims to test whether 10 …

Analysis of the thickness distribution varying tool trajectory in single-point incremental forming

L Manco, L Filice, G Ambrogio - Proceedings of the …, 2011 - journals.sagepub.com
Single-point incremental forming (SPIF) presents a great competitive advantage with respect
to the conventional stamping processes, in particular when small batches have to be …

A new PKLR gene mutation in the R‐type promoter region affects the gene transcription causing pyruvate kinase deficiency

L Manco, ML Ribeiro, V Máximo… - British journal of …, 2000 - Wiley Online Library
… in the presence of 4 mmol/l dNTPs, 1·0 U/μl RNAase Inhibitor, 2·5 μmol/l random primer P(dN)6 …
Total reaction volume was 25 μl, containing 25 pmol of PCR primers, 2 mmol/l dNTPs, 1x …