[HTML][HTML] CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

…, BJ Ainscough, CA Ramirez, DT Rieke, L Kujan… - Nature …, 2017 - nature.com
CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in
Cancer describing the therapeutic, prognostic, diagnostic and predisposing relevance of …

CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase

…, EK Barnell, L Sheta, CJ Grisdale, L Kujan… - Nucleic acids …, 2023 - academic.oup.com
CIViC (Clinical Interpretation of Variants in Cancer; civicdb.org) is a crowd-sourced, public
domain knowledgebase composed of literature-derived evidence characterizing the clinical …

[HTML][HTML] Standard operating procedure for curation and clinical interpretation of variants in cancer

…, S Kiwala, NC Spies, LM Sheta, SP Pema, L Kujan… - Genome medicine, 2019 - Springer
Manually curated variant knowledgebases and their associated knowledge models are
serving an increasingly important role in distributing and interpreting variants in cancer. These …

Large scale genotype‐and phenotype‐driven machine learning in Von Hippel‐Lindau disease

…, A Goldenberg, P Jani, K Krysiak, L Kujan… - Human …, 2022 - Wiley Online Library
Von Hippel‐Lindau (VHL) disease is a hereditary cancer syndrome where individuals are
predisposed to tumor development in the brain, adrenal gland, kidney, and other organs. It is …

Adapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community‐driven standards

…, JF McMichael, S Kiwala, AC Coffman, L Kujan… - Human …, 2018 - Wiley Online Library
Harmonization of cancer variant representation, efficient communication, and free distribution
of clinical variant‐associated knowledge are central problems that arise with increased …

CIViC: a knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer

…, BJ Ainscough, DT Rieke, AM Danos, L Kujan… - bioRxiv, 2016 - biorxiv.org
CIViC is an expert crowdsourced knowledgebase for Clinical Interpretation of Variants in
Cancer ( www.civicdb.org ) describing the therapeutic, prognostic, and diagnostic relevance of …

A community approach to the cancer-variant-interpretation bottleneck

…, EK Barnell, L Sheta, J Saliba, CJ Grisdale, L Kujan… - Nature cancer, 2022 - nature.com
As guidelines, therapies and literature on cancer variants expand, the lack of consensus
variant interpretations impedes clinical applications. CIViC is a public-domain, crowd-sourced …

Supplementation of ascorbic acid 2‐monophosphate during the early postlarval stages of the shrimp Penaeus vannamei

Lavens, Merchie, Ramos, ALH Kujan… - Aquaculture …, 1999 - Wiley Online Library
… They were stocked in 20 rectangular tanks of 50 L, at a density of 5 PL L −1 and kept in a …
Temperature and salinity of the oxygen-satu- rated seawater were kept at 28C and 35 g L −1 , …

Evolution of the open-access CIViC knowledgebase is driven by the needs of the cancer variant interpretation community

…, EK Barnell, L Sheta, J Saliba, CJ Grisdale, L Kujan… - bioRxiv, 2021 - biorxiv.org
CIViC (Clinical Interpretation of Variants in Cancer; civicdb.org ) is a crowd-sourced, public
domain knowledgebase composed of literature-derived evidence characterizing the clinical …

Use of the industrial yeastCandida utilis for cadmium sorption

P Kujan, A Prell, H Šafář, M Sobotka, T Řezanka… - Folia microbiologica, 2006 - Springer
… After an optimization of process conditions (pH 5.5, biomass concentration 1 g/L andc 0 50
mg/L), the cadmium sorption capacity of dried yeast biomass was perceptibly higher than that …