Microduplications of 16p11. 2 are associated with schizophrenia
…, VL Willour, P DeRosse, J Steele, L Kassem… - Nature …, 2009 - nature.com
Recurrent microdeletions and microduplications of a 600-kb genomic region of chromosome
16p11.2 have been implicated in childhood-onset developmental disorders 1 , 2 , 3 . We …
16p11.2 have been implicated in childhood-onset developmental disorders 1 , 2 , 3 . We …
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study
Background Lithium is a first-line treatment in bipolar disorder, but individual response is
variable. Previous studies have suggested that lithium response is a heritable trait. However, …
variable. Previous studies have suggested that lithium response is a heritable trait. However, …
Neurocognitive functioning in euthymic patients with bipolar disorder and unaffected relatives: a review of the literature
SA Cardenas, L Kassem, MA Brotman… - Neuroscience & …, 2016 - Elsevier
Background Neurocognitive deficits are present in bipolar disorder (BD) patients and their
unaffected (nonbipolar) relatives, but it is not clear which domains are most often impaired …
unaffected (nonbipolar) relatives, but it is not clear which domains are most often impaired …
Interleukins 1α and 6 and tumor necrosis factor-α are paracrine inhibitors of human melanocyte proliferation and melanogenesis
VB Swope, Z Abdel-Malek, LM Kassem… - Journal of investigative …, 1991 - Elsevier
Interleukin (IL)-1α, IL-6, and tumor necrosis factor (TNF)- α are epidermal cytokines that
produce many similar biologic effects. We have investigated the possibility that these cytokines …
produce many similar biologic effects. We have investigated the possibility that these cytokines …
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder
…, E Jiménez, JP Kahn, L Kassem… - Human molecular …, 2016 - academic.oup.com
Bipolar disorder (BD) is a genetically complex mental illness characterized by severe
oscillations of mood and behaviour. Genome-wide association studies (GWAS) have identified …
oscillations of mood and behaviour. Genome-wide association studies (GWAS) have identified …
Clinicopathologic Features of Breast Cancer in Egypt—Contemporary Profile and Future Needs: A Systematic Review and Meta-Analysis
…, M Abdelsalam, A Elzorkany, L Kassem - JCO Global …, 2023 - ascopubs.org
PURPOSE Breast cancer (BC) is the most common cancer among Egyptian females. No
current national cancer database is available in Egypt to provide reliable data on the specific …
current national cancer database is available in Egypt to provide reliable data on the specific …
Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder
…, JR Wendland, CJM Steele, L Kassem… - Molecular …, 2013 - nature.com
… HeLa, SH-SY5Y and HEK293 cells were grown in dulbecco's modified Eagles's medium
with 4.5 gm l –1 d-glucose supplemented with 2 mML-glutamine and 10% fetal calf serum. …
with 4.5 gm l –1 d-glucose supplemented with 2 mML-glutamine and 10% fetal calf serum. …
[HTML][HTML] Assessment of response to lithium maintenance treatment in bipolar disorder: a Consortium on Lithium Genetics (ConLiGen) report
Objective The assessment of response to lithium maintenance treatment in bipolar disorder (BD)
is complicated by variable length of treatment, unpredictable clinical course, and often …
is complicated by variable length of treatment, unpredictable clinical course, and often …
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
…, N Akula, A Gupta, L Kassem… - Molecular …, 2009 - nature.com
Two recent reports have highlighted ANK3 as a susceptibility gene for bipolar disorder (BD).
We first reported association between BD and the ANK3 marker rs9804190 in a genome-…
We first reported association between BD and the ANK3 marker rs9804190 in a genome-…
Personalized treatment in metastatic triple‐negative breast cancer: The outlook in 2020
Compared with other breast cancer subtypes, patients with triple‐negative breast cancer (TNBC),
and irrespective to their disease stage, were always recognized to have the worst …
and irrespective to their disease stage, were always recognized to have the worst …