Cholera toxin: a paradigm for multi-functional engagement of cellular mechanisms

L Haan, TR Hirst - Molecular membrane biology, 2004 - Taylor & Francis
Cholera toxin (Ctx) from Vibrio cholerae and its closely related homologue, heat-labile
enterotoxin (Etx) from Escherichia coli have become superb tools for illuminating pathways of …

[BOOK][B] Extreme value theory: an introduction

L Haan, A Ferreira - 2006 - Springer
Extreme Value Theory offers a careful, coherent exposition of the subject starting from the
probabilistic and mathematical foundations and proceeding to the statistical theory. The book …

Africa and China: A strategic partnership?

J Looy, L Haan - Strategic Analysis, 2006 - Taylor & Francis
Relations between Africa and China have increased over the years and become more
dominated by China's economic interests. With an annual growth rate of 8-9 per cent, and a …

Estimation of the marginal expected shortfall: the mean when a related variable is extreme

JJ Cai, JHJ Einmahl, L Haan… - Journal of the Royal …, 2015 - academic.oup.com
Denote the loss return on the equity of a financial institution as X and that of the entire market
as Y. For a given very small value of p > 0, the marginal expected shortfall (MES) is defined …

Statistics of heteroscedastic extremes

JHJ Einmahl, L Haan, C Zhou - Journal of the Royal Statistical …, 2016 - academic.oup.com
… ; set l 0 = 0 and l m = 1 ⁠. We use the partial Hill estimator γ ^ l j − 1 , l j as above but use the
highest [k/m]+1 observations in each subsample, since, by construction, C ^ ( l j ) − C ^ ( l j − …

Approximation by penultimate extreme value distributions

MI Gomes, LD Haan - Extremes, 1999 - Springer
… Lemma 3.3 from de Haan and Resnick (1996) holds without … The statement of Lemma 3.2
from de Haan and Resnick (1996) … With these alterations the proof of Theorem 3.1 in de Haan

Semi-parametric estimation of the second order parameter in statistics of extremes

MI Gomes, L Haan, L Peng - Extremes, 2002 - Springer
We present a class of semi-parametric estimators for the second order parameter related to
a probability distribution with a regularly varying tail. The second order parameter plays an …

[HTML][HTML] Predicting landscape configuration effects on agricultural pest suppression

NL Haan, Y Zhang, DA Landis - Trends in ecology & evolution, 2020 - cell.com
Arthropod predators and parasitoids attack crop pests, providing a valuable ecosystem service.
The amount of noncrop habitat surrounding crop fields influences pest suppression, but …

[HTML][HTML] Interstitial flow recapitulates gemcitabine chemoresistance in a 3D microfluidic pancreatic ductal adenocarcinoma model by induction of multidrug resistance …

B Kramer, L Haan, M Vermeer, T Olivier… - International Journal of …, 2019 - mdpi.com
Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most lethal cancers due to a high
chemoresistance and poor vascularization, which results in an ineffective systemic therapy. …

Design, construction and performance of a large tornado simulator for wind engineering applications

FL Haan Jr, PP Sarkar, WA Gallus - Engineering Structures, 2008 - Elsevier
A laboratory tornado simulator was designed, constructed and tested to generate tornado-like
vortices for the purpose of quantifying tornado-induced aerodynamic loads on civil …