SARS-CoV-2 can cause acute respiratory distress and death in some patients 1 . Although
severe COVID-19 is linked to substantial inflammation, how SARS-CoV-2 triggers …

Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK (…

The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly
developed for distribution and use in pandemic regions. Here, we report a pipeline for the …

Lateral flow assays (LFAs) are highly attractive for point-of-care (POC) diagnostics for infectious
disease, food safety, and many other medical uses. The unique optical, electronic, and …

Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …

… -4E (o, *), or pMV7/eIF-4E Ala 53 (L, A) were analyzed in parallel for eIF-4E, cyclin Dl, and
… We thank Vinita Adkar for excellent technical assistance and L. Maquat and M. Wilkinson for …

Blood cell formation is classically thought to occur through a hierarchical differentiation
process, although recent studies have shown that lineage commitment may occur earlier in …

… extended to bacterial infections, we returned to L. monocytogenes and Jeg3 cells, in which …
to L. monocytogenes infection. Indeed, in Jeg3 trophoblasts, where the interferon response to …

An expansion of the cerebral neocortex is thought to be the foundation for the unique intellectual
abilities of humans. It has been suggested that an increase in the proliferative potential …

Rapid point-of-care (POC) diagnostic devices are needed for field-forward screening of
severe acute systemic febrile illnesses. Multiplexed rapid lateral flow diagnostics have the …