Reconstructing historical variation of population size from sequence and single-nucleotide
polymorphism (SNP) data is valuable for understanding the evolutionary history of species. …

The history of click-speaking Khoe-San, and African populations in general, remains poorly
understood. We genotyped ∼2.3 million single-nucleotide polymorphisms in 220 southern …

Adaptation drives genomic changes; however, evidence of specific adaptations in humans
remains limited. We found that inhabitants of the northern Argentinean Andes, an arid region …

The southern African indigenous Khoe-San populations harbor the most divergent lineages
of all living peoples. Exploring their genomes is key to understanding deep human history. …

Introduction Uncovering safety signals through the collection and assessment of individual
case reports remains a core pharmacovigilance activity. Despite the widespread use of …

Approximate Bayesian computation ( ABC ) is a powerful tool for model‐based inference of
demographic histories from large genetic data sets. For most organisms, its implementation …

Characterizing the behavior and robustness of enzymatic networks with numerous variables
and unknown parameter values is a major challenge in biology, especially when some …

High-throughput genotyping and sequencing technologies can generate dense sets of genetic
markers for large numbers of individuals. For most species, these data will contain many …

Introduction A large number of studies on systems to detect and sometimes normalize adverse
events (AEs) in social media have been published, but evidence of their practical utility is …

Introduction and Objective Social media has been suggested as a source for safety information,
supplementing existing safety surveillance data sources. This article summarises the …