With a political debate about the potential risks and benefits of cannabis use as a backdrop,
the wave of legalization and liberalization initiatives continues to spread. Four states (…

The World Health Organization declared the coronavirus outbreak a pandemic on March 11,
2020. Infection by the SARS-CoV2 virus leads to the COVID-19 disease which can be fatal, …

… the community as previously selected for other studies (DeLisi et al. 1991) on the basis that
they were the same sex, age, and social class of consecutively obtained first episode patients…

Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Rare coding variation has historically provided the most direct connections between gene
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …

Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …

Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …

Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …

Recurrent microdeletions and microduplications of a 600-kb genomic region of chromosome
16p11.2 have been implicated in childhood-onset developmental disorders 1 , 2 , 3 . We …

Brain structural deviation is known to be present in chronic patients with schizophrenia
when compared with normal age-matched individuals. While the assumption is that these …