User profiles for L. Czech

Lucas Czech

- Verified email at sund.ku.dk - Cited by 1936

Laura Czech

- Verified email at biologie.uni-marburg.de - Cited by 588

[HTML][HTML] Role of the extremolytes ectoine and hydroxyectoine as stress protectants and nutrients: genetics, phylogenomics, biochemistry, and structural analysis

L Czech, L Hermann, N Stöveken, AA Richter… - Genes, 2018 - mdpi.com
Fluctuations in environmental osmolarity are ubiquitous stress factors in many natural habitats
of microorganisms, as they inevitably trigger osmotically instigated fluxes of water across …

UniEuk: Time to Speak a Common Language in Protistology!

…, DA Caron, G Cochrane, L Czech… - Journal of Eukaryotic …, 2017 - Wiley Online Library
Universal taxonomic frameworks have been critical tools to structure the fields of botany,
zoology, mycology, and bacteriology as well as their large research communities. Animals, …

EPA-ng: massively parallel evolutionary placement of genetic sequences

P Barbera, AM Kozlov, L Czech, B Morel… - Systematic …, 2019 - academic.oup.com
Next generation sequencing (NGS) technologies have led to a ubiquity of molecular sequence
data. This data avalanche is particularly challenging in metagenetics, which focuses on …

[HTML][HTML] Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells

C Yang, L Czech, S Gerboth, S Kojima, G Scita… - PLoS …, 2007 - journals.plos.org
Actin polymerization-driven protrusion of the leading edge is a key element of cell motility.
The important actin nucleators formins and the Arp2/3 complex are believed to have …

[HTML][HTML] Metagenomic analysis using phylogenetic placement—a review of the first decade

L Czech, A Stamatakis, M Dunthorn… - Frontiers in …, 2022 - frontiersin.org
Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and
interpret the tsunami of metagenomic sequencing data generated by high-throughput …

Genetic diversity loss in the Anthropocene

M Exposito-Alonso, TR Booker, L Czech, L Gillespie… - Science, 2022 - science.org
Anthropogenic habitat loss and climate change are reducing species’ geographic ranges,
increasing extinction risk and losses of species’ genetic diversity. Although preserving genetic …

Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α

…, L Czech, VJ Dudley, L Beussink… - American journal of …, 2014 - atsjournals.org
Rationale: Chronic hypoxia induces pulmonary vascular remodeling, pulmonary hypertension,
and right ventricular hypertrophy. At present, little is known about mechanisms driving …

Phylogenetic analysis of SARS-CoV-2 data is difficult

…, L Czech, B Bettisworth, L Hübner… - Molecular biology …, 2021 - academic.oup.com
Numerous studies covering some aspects of SARS-CoV-2 data analyses are being published
on a daily basis, including a regularly updated phylogeny on nextstrain.org. Here, we …

Parasites dominate hyperdiverse soil protist communities in Neotropical rainforests

F Mahé, C de Vargas, D Bass, L Czech… - Nature ecology & …, 2017 - nature.com
High animal and plant richness in tropical rainforest communities has long intrigued naturalists.
It is unknown if similar hyperdiversity patterns are reflected at the microbial scale with …

Genesis and Gappa: processing, analyzing and visualizing phylogenetic (placement) data

L Czech, P Barbera, A Stamatakis - Bioinformatics, 2020 - academic.oup.com
We present genesis, a library for working with phylogenetic data, and gappa, an accompanying
command-line tool for conducting typical analyses on such data. The tools target …