[HTML][HTML] A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
Beyond read-counts: Ribo-seq data analysis to understand the functions of the transcriptome
L Calviello, U Ohler - Trends in Genetics, 2017 - cell.com
By mapping the positions of millions of translating ribosomes in the cell, ribosome profiling (Ribo-seq)
has established its role as a powerful tool to study gene expression. Several …
has established its role as a powerful tool to study gene expression. Several …
Pressure autoregulation measurement techniques in adult traumatic brain injury, part II: a scoping review of continuous methods
A scoping review of the literature was performed systematically on commonly described
continuous autoregulation measurement techniques in adult traumatic brain injury (TBI) to …
continuous autoregulation measurement techniques in adult traumatic brain injury (TBI) to …
[PDF][PDF] The translational landscape of the human heart
Gene expression in human tissue has primarily been studied on the transcriptional level,
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …
Standardized annotation of translated open reading frames
To the Editor—Ribosome profiling (Ribo-seq) has extended our understanding of the
translational ‘vocabulary’of the human genome, uncovering thousands of open reading frames (…
translational ‘vocabulary’of the human genome, uncovering thousands of open reading frames (…
Detecting actively translated open reading frames in ribosome profiling data
RNA-sequencing protocols can quantify gene expression regulation from transcription to
protein synthesis. Ribosome profiling (Ribo-seq) maps the positions of translating ribosomes …
protein synthesis. Ribosome profiling (Ribo-seq) maps the positions of translating ribosomes …
[HTML][HTML] Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes
…, A Hirsekorn, L Calviello, L Simó-Riudalbas… - Nature …, 2020 - nature.com
Efforts to precisely identify tumor human leukocyte antigen (HLA) bound peptides capable
of mediating T cell-based tumor rejection still face important challenges. Recent studies …
of mediating T cell-based tumor rejection still face important challenges. Recent studies …
Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis
Deep sequencing of ribosome footprints (ribosome profiling) maps and quantifies mRNA
translation. Because ribosomes decode mRNA every 3 nt, the periodic property of ribosome …
translation. Because ribosomes decode mRNA every 3 nt, the periodic property of ribosome …
[HTML][HTML] Extensive identification and analysis of conserved small ORFs in animals
Background There is increasing evidence that transcripts or transcript regions annotated as
non-coding can harbor functional short open reading frames (sORFs). Loss-of-function …
non-coding can harbor functional short open reading frames (sORFs). Loss-of-function …
[HTML][HTML] RNA localization is a key determinant of neurite-enriched proteome
…, E McShane, M Moreno-Estelles, L Calviello… - Nature …, 2017 - nature.com
… media (L or H). iNeurons and mESC lysates were pooled (H iNeurons + L mESC for fw and
L mESC … The averages of H/L (fw) and L/H (rev) ratios were used to measure relative protein …
L mESC … The averages of H/L (fw) and L/H (rev) ratios were used to measure relative protein …