User profiles for L. Calviello

Lorenzo Calviello

- Verified email at fht.org - Cited by 6740

Dr. Leanne A. Calviello

- Verified email at cam.ac.uk - Cited by 504

[HTML][HTML] A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

…, R Rakesh, X Liu, SB Rosenthal, L Calviello… - Nature, 2020 - nature.com
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of coronavirus disease 2019 (COVID-19), has …

Beyond read-counts: Ribo-seq data analysis to understand the functions of the transcriptome

L Calviello, U Ohler - Trends in Genetics, 2017 - cell.com
By mapping the positions of millions of translating ribosomes in the cell, ribosome profiling (Ribo-seq)
has established its role as a powerful tool to study gene expression. Several …

Pressure autoregulation measurement techniques in adult traumatic brain injury, part II: a scoping review of continuous methods

FA Zeiler, J Donnelly, L Calviello… - Journal of …, 2017 - liebertpub.com
A scoping review of the literature was performed systematically on commonly described
continuous autoregulation measurement techniques in adult traumatic brain injury (TBI) to …

[PDF][PDF] The translational landscape of the human heart

…, M Kanda, CL Worth, S Schafer, L Calviello… - Cell, 2019 - cell.com
Gene expression in human tissue has primarily been studied on the transcriptional level,
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …

Standardized annotation of translated open reading frames

…, AA Bazzini, E Bruford, MJ Martin, L Calviello… - Nature …, 2022 - nature.com
To the Editor—Ribosome profiling (Ribo-seq) has extended our understanding of the
translational ‘vocabulary’of the human genome, uncovering thousands of open reading frames (…

Detecting actively translated open reading frames in ribosome profiling data

L Calviello, N Mukherjee, E Wyler, H Zauber… - Nature …, 2016 - nature.com
RNA-sequencing protocols can quantify gene expression regulation from transcription to
protein synthesis. Ribosome profiling (Ribo-seq) maps the positions of translating ribosomes …

[HTML][HTML] Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes

…, A Hirsekorn, L Calviello, L Simó-Riudalbas… - Nature …, 2020 - nature.com
Efforts to precisely identify tumor human leukocyte antigen (HLA) bound peptides capable
of mediating T cell-based tumor rejection still face important challenges. Recent studies …

Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis

PY Hsu, L Calviello, HYL Wu, FW Li… - Proceedings of the …, 2016 - National Acad Sciences
Deep sequencing of ribosome footprints (ribosome profiling) maps and quantifies mRNA
translation. Because ribosomes decode mRNA every 3 nt, the periodic property of ribosome …

[HTML][HTML] Extensive identification and analysis of conserved small ORFs in animals

…, H Zauber, C Bielow, D Thiel, K Kutz, L Calviello… - Genome biology, 2015 - Springer
Background There is increasing evidence that transcripts or transcript regions annotated as
non-coding can harbor functional short open reading frames (sORFs). Loss-of-function …

[HTML][HTML] RNA localization is a key determinant of neurite-enriched proteome

…, E McShane, M Moreno-Estelles, L Calviello… - Nature …, 2017 - nature.com
… media (L or H). iNeurons and mESC lysates were pooled (H iNeurons + L mESC for fw and
L mESC … The averages of H/L (fw) and L/H (rev) ratios were used to measure relative protein …