▪ Abstract We review how motile cells regulate actin filament assembly at their leading edge.
Activation of cell surface receptors generates signals (including activated Rho family …

… p , for N filaments that are in a non-crosslinked bundle this becomes F B = N(π 2 K B T/L 2
)l … bundle reads L p = Nl p for filaments freely able to slide over each other and L p = N 2 l p …

Actin dynamics, or the rapid turnover of actin filaments, play a central role in numerous
cellular processes. A large and diverse cast of characters, accessory proteins known as actin-…

The Arp2/3 complex, a stable assembly of two actin-related proteins (Arp2 and Arp3) with five
other subunits, caps the pointed end of actin filaments and nucleates actin polymerization …

Most nucleated cells crawl about by extending a pseudopod that is driven by the polymerization
of actin filaments in the cytoplasm behind the leading edge of the plasma membrane 1 , …

We characterized the interaction ofAcanthamoeba actophorin, a member of ADF/cofilin family,
with filaments of amoeba and rabbit skeletal muscle actin. The affinity is about 10 times …

The organization of actin filaments into higher-ordered structures governs eukaryotic cell
shape and movement. Global actin network size and architecture are maintained in a dynamic …

Background: Cellular movements are powered by the assembly and disassembly of actin
filaments. Actin dynamics are controlled by Arp2/3 complex, the Wiskott–Aldrich syndrome …

… We calculated the scaled fit parameter ω/L for microtubules with varying parameters of
the perturbation Δs/L and κ p /κ 0 and different ratios κ 0 /L 3 gηv, corresponding to different …

We determined the flexural (bending) rigidities of actin and cofilactin filaments from a cosine
correlation function analysis of their thermally driven, two-dimensional fluctuations in shape. …