Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

L Beccari, N Moris, M Girgin, DA Turner… - Nature, 2018 - nature.com
The emergence of multiple axes is an essential element in the establishment of the mammalian
body plan. This process takes place shortly after implantation of the embryo within the …

[PDF][PDF] Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex

B Cubelos, A Sebastián-Serrano, L Beccari… - Neuron, 2010 - cell.com
Dendrite branching and spine formation determines the function of morphologically distinct
and specialized neuronal subclasses. However, little is known about the programs instructing …

[HTML][HTML] The logic of gene regulatory networks in early vertebrate forebrain patterning

L Beccari, R Marco-Ferreres, P Bovolenta - Mechanisms of development, 2013 - Elsevier
The vertebrate forebrain or prosencephalon is patterned at the beginning of neurulation into
four major domains: the telencephalic, hypothalamic, retinal and diencephalic anlagen. …

The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes

…, Y Zhan, PJ Fabre, L Beccari… - Genes & …, 2017 - genesdev.cshlp.org
The mammalian HoxD cluster lies between two topologically associating domains (TADs)
matching distinct enhancer-rich regulatory landscapes. During limb development, the …

Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders

…, I Maeso, L Beccari… - Proceedings of the …, 2015 - National Acad Sciences
Increasing evidence in the last years indicates that the vast amount of regulatory information
contained in mammalian genomes is organized in precise 3D chromatin structures. …

[HTML][HTML] The transcription factor encyclopedia

…, R Marco-Ferreres, JJ Brosens, LL Beccari… - Genome biology, 2012 - Springer
Here we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium
of mini review articles on transcription factors (TFs) that is founded on the principles of …

Phosphorylated filamin A regulates actin-linked caveolae dynamics

…, C Hellriegel, DM Pavón, L Beccari… - Journal of cell …, 2011 - journals.biologists.com
… (L) FLNa is required for CTxB uptake in HeLa cells. HeLa-shFLNa and HeLa-shLuc cells
were incubated with CTxB at 4C and maintained in suspension as indicated. Wheat germ …

Towards adaptive deep brain stimulation: clinical and technical notes on a novel commercial device for chronic brain sensing

…, JF Bally, E Manferlotti, L Beccaria… - Journal of Neural …, 2021 - iopscience.iop.org
Objective. Technical advances in deep brain stimulation (DBS) are crucial to improve
therapeutic efficacy and battery life. We report the potentialities and pitfalls of one of the first …

[HTML][HTML] An evolutionarily-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra

MC Vogg, L Beccari, L Iglesias Ollé, C Rampon… - Nature …, 2019 - nature.com
Polyps of the cnidarian Hydra maintain their adult anatomy through two developmental
organizers, the head organizer located apically and the foot organizer basally. The head …

A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus

L Beccari, N Yakushiji-Kaminatsui… - Genes & …, 2016 - genesdev.cshlp.org
During vertebrate limb development, Hoxd genes are regulated following a bimodal strategy
involving two topologically associating domains (TADs) located on either side of the gene …