User profiles for L. Anavy

leon anavy

IDC Herzliya
Verified email at post.idc.ac.il
Cited by 1683

[HTML][HTML] CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq

…, G Avital, A Klochendler, Y De Leeuw, L Anavy… - Genome biology, 2016 - Springer
Single-cell transcriptomics requires a method that is sensitive, accurate, and reproducible.
Here, we present CEL-Seq2, a modified version of our CEL-Seq method, with threefold higher …

The mid-developmental transition and the evolution of animal body plans

M Levin, L Anavy, AG Cole, E Winter, N Mostov, S Khair… - Nature, 2016 - nature.com
Animals are grouped into ~35 ‘phyla’ based upon the notion of distinct body plans 1 , 2 , 3 ,
4 . Morphological and molecular analyses have revealed that a stage in the middle of …

Data storage in DNA with fewer synthesis cycles using composite DNA letters

L Anavy, I Vaknin, O Atar, R Amit, Z Yakhini - Nature biotechnology, 2019 - nature.com
… In accordance with the theoretical analysis, Kullback–Leibler inference also performed much
better than L 1 norm inference on the experimental data (Supplementary Figs. 14 and 15). …

[HTML][HTML] CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

…, D Breier, N Ben Haim, Y Wang, L Anavy… - Nature …, 2021 - nature.com
… We count all the L Tx reads that are classified as originating from an edit event (in at least
one position) and calculate their proportion from the total reads at λ, as well as a confidence …

BLIND ordering of large-scale transcriptomic developmental timecourses

L Anavy, M Levin, S Khair, N Nakanishi… - …, 2014 - journals.biologists.com
RNA-Seq enables the efficient transcriptome sequencing of many samples from small
amounts of material, but the analysis of these data remains challenging. In particular, in …

SOLQC: Synthetic oligo library quality control tool

O Sabary, Y Orlev, R Shafir, L Anavy, E Yaakobi… - …, 2021 - academic.oup.com
Motivation Recent years have seen a growing number and an expanding scope of studies
using synthetic oligo libraries for a range of applications in synthetic biology. As experiments …

[PDF][PDF] A synthetic oligo library and sequencing approach reveals an insulation mechanism encoded within bacterial σ54 promoters

L Levy, L Anavy, O Solomon, R Cohen… - Cell Reports, 2017 - cell.com
We use an oligonucleotide library of >10,000 variants to identify an insulation mechanism
encoded within a subset of σ 54 promoters. Insulation manifests itself as reduced protein …

The gene regulatory program of Acrobeloides nanus reveals conservation of phylum-specific expression

…, DH Silver, V Grishkevich, L Anavy… - Proceedings of the …, 2018 - National Acad Sciences
The evolution of development has been studied through the lens of gene regulation by
examining either closely related species or extremely distant animals of different phyla. In …

Sequencing coverage analysis for combinatorial DNA-based storage systems

I Preuss, B Galili, Z Yakhini, L Anavy - bioRxiv, 2024 - biorxiv.org
… using 𝑙 combinatorial sequences and, assuming proper MDS error correction code, 𝑎 ≤ 𝑙
of … probability of decoding at least 𝑎 of 𝑙 sequence using 𝑅𝑎𝑙𝑙 reads, 𝑃𝑎𝑙𝑙(𝑅𝑎𝑙𝑙, 𝑙, 𝑎). …

[HTML][HTML] Molecular harvesting with electroporation for tissue profiling

A Golberg, J Sheviryov, O Solomon, L Anavy… - Scientific Reports, 2019 - nature.com
… Leon Anavy thanks the generous support of the Technion and of the Adams Fellowship.
All authors thank the members of Smoler Proteomics Center Faculty of Biology especially to …