Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …

Background The burden and influence of health-care associated severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …

HCV is a blood‐borne pathogen that affects approximately 3% of the global population and
leads to progressive liver disease. Recent advances have identified an essential role for host …

The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …

Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent
transmission. In this study we use a novel infectious coculture system to examine these …

BACKGROUND & AIMS: Hepatitis C virus (HCV) infection leads to progressive liver disease
and is associated with a variety of extrahepatic syndromes, including central nervous …

We report on an Ebola virus disease (EVD) survivor who showed Ebola virus in seminal fluid
531 days after onset of disease. The persisting virus was sexually transmitted in February …

Monitoring the spread of SARS-CoV-2 and reconstructing transmission chains has become
a major public health focus for many governments around the world. The modest mutation …

A recent outbreak of Zika virus in Brazil has led to a simultaneous increase in reports of
neonatal microcephaly. Zika targets cerebral neural precursors, a cell population essential for …

The structural flexibility of RNA underlies fundamental biological processes, but there are no
methods for exploring the multiple conformations adopted by RNAs in vivo. We developed …