… Hillier, John D. McPherson, Marco A. Marra, Elaine R. …

… We leave examples of this to the reader (see Hillier and Armstrong (1996) for the regression
example), and briefly discuss here a well-known example in which the MLE is uniquely …

Present-day DNA sequencing techniques have evolved considerably from their early
beginnings. A modern sequencing project is essentially an assembly-line environment and is …

Generating meaningful interpretations of gene lists remains a challenge for all large-scale
studies. Many approaches exist, often based on evaluating gene enrichment among pre-…

What constraints govern the evolution of gene expression patterns across development
remains a fundamental question of evolutionary biology. The advent of single-cell sequencing …

The comparative analysis of the related nematodes Caenorhabditis elegans and C. briggsae
offers a powerful approach toward understanding the genetic basis for the form and …

The principal steps in the DNA sequence process are listed along with examples of early
contributions to improvements to the process. The continual improvement of each step has …

ZP4 (ZP1-like): The polypeptide of ZP4 consists of 527 aa residues and has an SS (aa 1–15;
highlighted), a trefoil domain (aa 138–180; italicized) with six Cys residues (aa 140, 150, …

Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma
mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global …

We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme
exhibits a fascinating combination of reptilian and mammalian characters. For example…