User profiles for L. S. Tirrell

Lee S Tirrell

Software Engineer, CorticoMetrics
Verified email at corticometrics.com
Cited by 848

[HTML][HTML] 7 Tesla MRI of the ex vivo human brain at 100 micron resolution

…, JP Stockmann, BR Diamond, A Stevens, LS Tirrell… - Scientific data, 2019 - nature.com
We present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The
brain specimen was donated by a 58-year-old woman who had no history of neurological …

Multimodal characterization of the late effects of traumatic brain injury: a methodological overview of the late effects of traumatic brain injury project

…, KR Richmire, A Stevens, CY Tang, LS Tirrell… - Journal of …, 2018 - liebertpub.com
Epidemiological studies suggest that a single moderate-to-severe traumatic brain injury (TBI)
is associated with an increased risk of neurodegenerative disease, including Alzheimer's …

Dementia after moderate-severe traumatic brain injury: coexistence of multiple proteinopathies

…, A Stevens, AL Moreau, LS Tirrell… - … of Neuropathology & …, 2018 - academic.oup.com
We report the clinical, neuroimaging, and neuropathologic characteristics of 2 patients who
developed early onset dementia after a moderate-severe traumatic brain injury (TBI). …

[HTML][HTML] Multidimensional heritability analysis of neuroanatomical shape

…, AM Winkler, AJ Holmes, PH Lee, LS Tirrell… - Nature …, 2016 - nature.com
In the dawning era of large-scale biomedical data, multidimensional phenotype vectors will
play an increasing role in examining the genetic underpinnings of brain features, behaviour …

as-PSOCT: Volumetric microscopic imaging of human brain architecture and connectivity

…, C Magnain, R Wang, J Dubb, A Varjabedian, LS Tirrell… - Neuroimage, 2018 - Elsevier
Polarization sensitive optical coherence tomography (PSOCT) with serial sectioning has
enabled the investigation of 3D structures in mouse and human brain tissue samples. By using …

[HTML][HTML] PyBIDS: Python tools for BIDS datasets

…, K Whitaker, E DuPre, A Wagner, LS Tirrell… - Journal of open …, 2019 - ncbi.nlm.nih.gov
Brain imaging researchers regularly work with large, heterogeneous, high-dimensional datasets.
Historically, researchers have dealt with this complexity idiosyncratically, with every lab …

Polymer self-diffusion in entangled systems

M Tirrell - Rubber chemistry and technology, 1984 - meridian.allenpress.com
This article has focused on work in the last several years, a period during which theoretical
insights and experimental techniques pertaining to polymer self-diffusion in entangled …

Heritability of neuroanatomical shape

…, M Reuter, AM Winkler, AJ Holmes, PH Lee, LS Tirrell… - BioRxiv, 2015 - biorxiv.org
Measurements from structural brain magnetic resonance imaging (MRI) scans have been
increasingly analyzed as intermediate phenotypes to bridge the gap between clinical features …

Role of deleted in liver cancer 2 (DLC2) in diabetes-associated neuropathy

R Feng, LS Tirrell, SK Chung - Neuroscience Symposium & HKSN 2016 …, 2016 - hub.hku.hk
Diabetes mellitus (DM), characterized by hyperglycemia, represents one of the main threats
to human health in the 21st century. One of the major complications of diabetes is diabetic …

The role of RhoA GTPase activating protein DLC2 in painful diabetic neuropathy

LS Tirrell - HKU Theses Online (HKUTO), 2013 - hub.hku.hk
Neuropathy is a major complication that affects nearly half of all patients with diabetes, greatly
decreasing their quality of life. Patients experience a wide range of symptoms including …