The Illumina DNA sequencing platform generates accurate but short reads, which can be used
to produce accurate but fragmented genome assemblies. Pacific Biosciences and Oxford …

Background Basecalling, the computational process of translating raw electrical signal to
nucleotide sequence, is of critical importance to the sequencing platforms produced by Oxford …

Illumina sequencing platforms have enabled widespread bacterial whole genome sequencing.
While Illumina data is appropriate for many analyses, its short read length limits its ability …

Cytokine signalling pathways that depend on gp130 are dysregulated in several epithelial
cancers including gastric cancer. It has been established that blockade of SHP2 activation of …

… Franic TV, Judd LM, Robinson D, Regulation of gastric epithelial cell development revealed
in H(+)/K(+)-ATPase beta-subunit- and gastrin-deficient mice. Am J Physiol Gastrointest …

While long-read sequencing allows for the complete assembly of bacterial genomes, long-read
assemblies contain a variety of errors. Here, we present Trycycler, a tool which produces …

The latent transcription factor Stat3 is activated by gp130, the common receptor for the
interleukin (IL)-6 cytokine family and other growth factor and cytokine receptors. Ligand-induced …

Purpose To examine patterns of use, efficacy, and safety of intravenous ketamine for the
treatment of refractory status epilepticus ( RSE ). Methods Multicenter retrospective review of …

Mobile genetic elements (MGEs) that frequently transfer within and between bacterial
species play a critical role in bacterial evolution, and often carry key accessory genes that …

Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases (…