User profiles for L. F. Pallares
 | Luisa F PallaresFriedrich Miescher Laboratory of the Max Planck Society Verified email at tuebingen.mpg.de Cited by 371 |
[HTML][HTML] Mapping of craniofacial traits in outbred mice identifies major developmental genes involved in shape determination
The vertebrate cranium is a prime example of the high evolvability of complex traits. While
evidence of genes and developmental pathways underlying craniofacial shape determination …
evidence of genes and developmental pathways underlying craniofacial shape determination …
Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila
Evolutionary theory suggests that lifespan-reducing alleles should be purged from the gene
pool, and yet decades of genome-wide association and model organism studies have …
pool, and yet decades of genome-wide association and model organism studies have …
Use of a natural hybrid zone for genomewide association mapping of craniofacial traits in the house mouse
The identification of the genes involved in morphological variation in nature is still a major
challenge. Here, we explore a new approach: we combine 178 samples from a natural hybrid …
challenge. Here, we explore a new approach: we combine 178 samples from a natural hybrid …
TM3'seq: A tagmentation-mediated 3'sequencing approach for improving scalability of RNAseq experiments
LF Pallares, S Picard, JF Ayroles - G3: Genes, Genomes …, 2020 - academic.oup.com
RNA-seq has become the standard tool for collecting genome-wide expression data in diverse
fields, from quantitative genetics and medical genomics to ecology and developmental …
fields, from quantitative genetics and medical genomics to ecology and developmental …
The structure of behavioral variation within a genotype
…, A Bravin, K Skutt-Kakaria, P Reimers, LF Pallares… - Elife, 2021 - elifesciences.org
Individual animals vary in their behaviors. This is true even when they share the same
genotype and were reared in the same environment. Clusters of covarying behaviors constitute …
genotype and were reared in the same environment. Clusters of covarying behaviors constitute …
Exploring the effects of gene dosage on mandible shape in mice as a model for studying the genetic basis of natural variation
Mandible shape in the mouse is a complex trait that is influenced by many genetic factors.
However, little is known about the action of single genes on adult mandible shape so far, since …
However, little is known about the action of single genes on adult mandible shape so far, since …
[HTML][HTML] Craniofacial shape transition across the house mouse hybrid zone: implications for the genetic architecture and evolution of between-species differences
… Two hundred forty nine mice were used in this study; a subset of them was previously used
in genome-wide association studies of craniofacial (Pallares et al. 2014) and sterility traits (…
in genome-wide association studies of craniofacial (Pallares et al. 2014) and sterility traits (…
[HTML][HTML] Searching for solutions to the missing heritability problem
LF Pallares - elife, 2019 - elifesciences.org
Rare genetic variants in yeast explain a large amount of phenotypic variation in a complex
trait like growth.
trait like growth.
[HTML][HTML] Mouse skull mean shape and shape robustness rely on different genetic architectures and different loci
The genetic architecture of skull shape has been extensively studied in mice and the results
suggest a highly polygenic and additive basis. In contrast few studies have explored the …
suggest a highly polygenic and additive basis. In contrast few studies have explored the …
Saturating the eQTL map in Drosophila melanogaster: genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populations
Decades of genome-wide mapping have shown that most genetic polymorphisms associated
with complex traits are found in non-coding regions of the genome. Characterizing the …
with complex traits are found in non-coding regions of the genome. Characterizing the …