User profiles for L. A. Rettberg

Lee Rettberg

Postdoc, ETH Zurich
Verified email at mol.biol.ethz.ch
Cited by 768

Bdellovibrio predation cycle characterized at nanometre-scale resolution with cryo-electron tomography

…, AI Jewett, S Kreida, P Dutka, LA Rettberg… - Nature …, 2023 - nature.com
Bdellovibrio bacteriovorus is a microbial predator that offers promise as a living antibiotic for
its ability to kill Gram-negative bacteria, including human pathogens. Even after six decades …

[PDF][PDF] In vivo structures of the Helicobacter pylori cag type IV secretion system

YW Chang, CL Shaffer, LA Rettberg, D Ghosal… - Cell Reports, 2018 - cell.com
The type IV secretion system (T4SS) is a versatile nanomachine that translocates diverse
effector molecules between microbes and into eukaryotic cells. Here, using electron …

In vivo structures of an intact type VI secretion system revealed by electron cryotomography

YW Chang, LA Rettberg, DR Ortega, GJ Jensen - EMBO reports, 2017 - embopress.org
The type VI secretion system (T6 SS ) is a versatile molecular weapon used by many
bacteria against eukaryotic hosts or prokaryotic competitors. It consists of a cytoplasmic …

Cluster assembly in nitrogenase

NS Sickerman, LA Rettberg, CC Lee, Y Hu… - Essays in …, 2017 - portlandpress.com
The versatile enzyme system nitrogenase accomplishes the challenging reduction of N 2 and
other substrates through the use of two main metalloclusters. For molybdenum nitrogenase…

Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography

…, G Kovacikova, JA Sutherland, LA Rettberg… - Nature …, 2017 - nature.com
Type IV pili (T4P) are filamentous appendages found on many Bacteria and Archaea. They
are helical fibres of pilin proteins assembled by a multi-component macromolecular machine …

[HTML][HTML] Probing the coordination and function of Fe4S4 modules in nitrogenase assembly protein NifB

LA Rettberg, J Wilcoxen, CC Lee, MT Stiebritz… - Nature …, 2018 - nature.com
NifB is an essential radical S-adenosylmethionine (SAM) enzyme for nitrogenase cofactor
assembly. Previous studies show that NifB couples a putative pair of [Fe 4 S 4 ] modules (…

X‐Ray Crystallographic Analysis of NifB with a Full Complement of Clusters: Structural Insights into the Radical SAM‐Dependent Carbide Insertion During …

W Kang, LA Rettberg, MT Stiebritz… - Angewandte Chemie …, 2021 - Wiley Online Library
NifB is an essential radical SAM enzyme required for the assembly of an 8Fe core of the
nitrogenase cofactor. Herein, we report the X‐ray crystal structures of Methanobacterium …

[HTML][HTML] Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB

LA Rettberg, J Wilcoxen, AJ Jasniewski, CC Lee… - Nature …, 2020 - nature.com
NifB is a radical S-adenosyl-L-methionine (SAM) enzyme that is essential for nitrogenase
cofactor assembly. Previously, a nitrogen ligand was shown to be involved in coupling a pair of …

Structural Analysis of a Nitrogenase Iron Protein from Methanosarcina acetivorans: Implications for CO2 Capture by a Surface-Exposed [Fe4S4] Cluster

LA Rettberg, W Kang, MT Stiebritz, CJ Hiller, CC Lee… - Mbio, 2019 - Am Soc Microbiol
Nitrogenase iron (Fe) proteins reduce CO 2 to CO and/or hydrocarbons under ambient
conditions. Here, we report a 2.4-Å crystal structure of the Fe protein from Methanosarcina …

Strategies towards capturing nitrogenase substrates and intermediates via controlled alteration of electron fluxes

…, CC Lee, MT Stiebritz, LA Rettberg… - … –A European Journal, 2019 - Wiley Online Library
Nitrogenase utilizes an ATP‐dependent reductase to deliver electrons to its catalytic component
to enable two important reactions: the reduction of N 2 to NH 4 + , and the reduction of …