User profiles for K. van de Groep

Kirsten van de Groep

Umcu
Verified email at umcutrecht.nl
Cited by 326

Immunosenescence and pneumococcal disease: an imbalance in host–pathogen interactions

CL Krone, K van de Groep, K Trzciński… - The lancet Respiratory …, 2014 - thelancet.com
Respiratory infections are among the most important causes of morbidity and mortality from
infectious diseases worldwide. The most common causative bacterium, Streptococcus …

Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study

…, ME Koster-Brouwer, K van de Groep… - The Lancet …, 2017 - thelancet.com
… correlation distances, 99% item (sample) resampling, 1000 iterations, and cluster range k=2–12.
To estimate k (number of endotypes), we combined cumulative distribution functions, …

Myocardial injury in patients with sepsis and its association with long-term outcome

…, PMC Klein Klouwenberg, K van de Groep… - … Quality and Outcomes, 2018 - Am Heart Assoc
Background: Sepsis is frequently complicated by the release of cardiac troponin, but the
clinical significance of this myocardial injury remains unclear. We studied the associations …

Associations between enteral colonization with gram-negative bacteria and intensive care unit–acquired infections and colonization of the respiratory tract

…, NL Plantinga, C Spitoni, K van de Groep… - Clinical Infectious …, 2018 - academic.oup.com
… In a recently published study, though, it was concluded based on whole-genome sequencing
results that in 80% of infections, the genome of K. pneumoniae was identical to that of the K

Epidemiology and outcomes of source control procedures in critically ill patients with intra-abdominal infection

K van de Groep, TL Verhoeff, DM Verboom, LD Bos… - Journal of critical …, 2019 - Elsevier
Purpose To describe the characteristics and procedural outcomes of source control interventions
among Intensive Care Unit (ICU) patients with severe intra-abdominal-infection (IAI). …

[HTML][HTML] Iron metabolism in critically ill patients developing anemia of inflammation: a case control study

…, JM Binnekade, B Nota, K van de Groep… - Annals of intensive …, 2018 - Springer
Background Anemia occurring as a result of inflammatory processes (anemia of
inflammation, AI) has a high prevalence in critically ill patients. Knowledge on changes in iron …

[HTML][HTML] Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with …

K Van De Groep, MP Bos, PHM Savelkoul… - European Journal of …, 2018 - Springer
Molecular tests may enable early adjustment of antimicrobial therapy and be complementary
to blood culture (BC) which has imperfect sensitivity in critically ill patients. We evaluated a …

[PDF][PDF] Defining host responses during systemic bacterial infection through construction of a murine organ proteome atlas

…, A Campeau, RH Fang, X Wei, K van de Groep… - Cell systems, 2018 - cell.com
Group A Streptococcus (GAS) remains one of the top 10 deadliest human pathogens
worldwide despite its sensitivity to penicillin. Although the most common GAS infection is …

Consumptive coagulopathy is associated with a disturbed host response in patients with sepsis

…, ME Koster‐Brouwer, K van de Groep… - … of Thrombosis and …, 2021 - Wiley Online Library
… Exclusion criteria were: the absence of a PT measurement or intravenous administration of
heparin in the first 24 h after ICU admission, chronic use of a vitamin K antagonist prior to ICU …

[HTML][HTML] Detection of invasive aspergillosis in critically ill patients with influenza: the role of plasma galactomannan

K van de Groep, DM Verboom… - American Journal of …, 2019 - atsjournals.org
Invasive pulmonary aspergillosis (IPA) is a complication of influenza infection that has been
associated with 33-67% mortality (1-3). In a recent cohort of patients with severe …