The emerging field of regenerative medicine offers innovative methods of cell therapy and
tissue/organ engineering as a novel approach to liver disease treatment. The ultimate …

Background Alcohol abuse has deleterious effects on human health by disrupting the functions
of many organs and systems. Gut microbiota has been implicated in the pathogenesis of …

Glioma is the most common type of primary CNS tumor, composed of cells that resemble
normal glial cells. Recent genetic studies have provided insight into the inter-tumoral …

Chronic liver diseases constitute a significant economic, social, and biomedical burden.
Among commonly adopted approaches, only organ transplantation can radically help patients …

The middle cerebral artery occlusion (MCAO) model in rats closely imitates ischemic stroke
and is widely used. Existing instrumental methods provide a certain level of MCAO guidance, …

Stem cells serve as a source of cellular material in embryogenesis and postnatal growth and
regeneration. This requires significant proliferative potential ensured by sufficient telomere …

Cell therapy is an emerging approach to stroke treatment with a potential to limit brain damage
and enhance its restoration after the acute phase of the disease. In this study we tested …

Animal model studies and first clinical trials have demonstrated the safety and efficacy of the
mesenchymal stem cells’ (MSCs) transplantation in stroke. Intra-arterial (IA) administration …

Neutrophil microparticles (NMs) are scarce in the circulation but are highly enriched at sites
of inflammation and exert profound effects on immune cells. In the present study, we …

We performed a comparative study of the proliferative potential of human mesenchymal
stromal cells (MSC) from three sources (tooth pulp, adipose tissue, and Wharton’s jelly) in …