Splenic marginal zone lymphoma proposals for a revision of diagnostic, staging and therapeutic criteria

…, ED Remstein, A Salar, F Solé, K Stamatopoulos… - Leukemia, 2008 - nature.com
Since the initial description of splenic marginal zone lymphoma (SMZL) in 1992, an increasing
number of publications have dealt with multiple aspects of SMZL diagnosis, molecular …

Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation

…, N Chiorazzi, K Stamatopoulos - Journal of internal …, 2008 - Wiley Online Library
Several studies suggest that immune‐mediated pathways are important in the pathogenesis
of chronic lymphocytic leukaemia (CLL). The in vivo accumulation of leukaemic …

[HTML][HTML] ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—update on methodological approaches and results interpretation

…, C Moreno, G Gaidano, K Stamatopoulos… - Leukemia, 2018 - nature.com
In chronic lymphocytic leukemia (CLL), TP53 gene defects, due to deletion of the 17p13
locus and/or mutation(s) within the TP53 gene, are associated with resistance to …

Non-coding recurrent mutations in chronic lymphocytic leukaemia

…, M Rozman, N Russiñol, I Salaverría, K Stamatopoulos… - Nature, 2015 - nature.com
Chronic lymphocytic leukaemia (CLL) is a frequent disease in which the genetic alterations
determining the clinicobiological behaviour are not fully understood. Here we describe a …

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations

K Stamatopoulos, C Belessi, C Moreno, M Boudjograh… - Blood, 2007 - ashpublications.org
The chronic lymphocytic leukemia (CLL) immunoglobulin repertoire is biased and
characterized by the existence of subsets of cases with closely homologous (“stereotyped”) …

Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

…, P Ghia, K Stamatopoulos - Blood, The Journal …, 2012 - ashpublications.org
… Anagnostopoulos, HM-B., NL, GJ, SP, and JJ provided samples and associated clinicopathologic
data and supervised research; and K. Stamatopoulos designed the study, supervised …

Human memory B cells originate from three distinct germinal center-dependent and-independent maturation pathways

…, K Stamatopoulos… - Blood, The Journal …, 2011 - ashpublications.org
Multiple distinct memory B-cell subsets have been identified in humans, but it remains
unclear how their phenotypic diversity corresponds to the type of responses from which they …

The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation

…, S Rasi, L Laurenti, K Stamatopoulos… - Blood, The Journal …, 2011 - ashpublications.org
Richter syndrome (RS) represents the development of diffuse large B-cell lymphoma in the
context of chronic lymphocytic leukemia. The scarcity of biologic information about RS has …

Recurrent mutations refine prognosis in chronic lymphocytic leukemia

…, G Gaidano, E Campo, JC Strefford, K Stamatopoulos… - Leukemia, 2015 - nature.com
Through the European Research Initiative on chronic lymphocytic leukemia (CLL)(ERIC),
we screened 3490 patients with CLL for mutations within the NOTCH1 (n= 3334), SF3B1 (n= …

Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in …

…, F Davi, R Rosenquist, K Stamatopoulos - Blood, The Journal …, 2008 - ashpublications.org
Somatic hypermutation (SHM) features in a series of 1967 immunoglobulin heavy chain
gene (IGH) rearrangements obtained from patients with chronic lymphocytic leukemia (CLL) …