The principles of self-assembly and self-organization are major tenets of molecular and cellular
biology. Governed by these principles, the eukaryotic nucleus is composed of numerous …

INTRODUCTION Large-scale genetic studies of integrated health care populations, with
phenotypic data captured natively in the documentation of clinical care, have the potential to …

A healthy periodontium is vital for the general well-being of an individual. However,
periodontal diseases are common and periodontal infections are increasingly associated with …

Primary ciliary dyskinesia (PCD) is a ciliopathy, but represents the sole entity from this class
of disorders that results from the dysfunction of motile cilia. Characterized by respiratory …

The UK Biobank is a prospective study of 502,543 individuals, combining extensive phenotypic
and genotypic data with streamlined access for researchers around the world 1 . Here …

Objectives: To find out whether hypotensive anaesthesia minimized blood loss during
orthognathic surgery. Design: A prospective randomized clinical study. Subjects and methods: 53 …

T cell anergy has been correlated with defective signaling by the GTPase Ras, but causal
and mechanistic data linking defective Ras activity with T cell anergy are lacking. Here we …

The objective of this study was to characterize the response of golden shiner fed one of
eight purified diets with either 0 or 38 mg α-tocopherol (α-T) kg −1 and one of four levels of …

The UK Biobank is a prospective study of 502,543 individuals, combining extensive phenotypic
and genotypic data with streamlined access for researchers around the world. Here we …

Primary ciliary dyskinesia (PCD) is a recessively inherited disease that leads to chronic
respiratory disorders owing to impaired mucociliary clearance. Conventional transmission …