The scale of genetic, epigenomic, transcriptomic, cheminformatic and proteomic data
available today, coupled with easy-to-use machine learning (ML) toolkits, has propelled the …

Inhalation of dust containing crystalline silica is associated with a number of acute and
chronic diseases including systemic autoimmune diseases. Evidence for the link with …

The term interferon describes a family of proteins consisting of three major types (I, II, III)
which differ in their primary protein sequences, cognate receptors, genetic loci, and cell types …

Methods for detecting nucleotide substitution rates that are faster or slower than expected
under neutral drift are widely used to identify candidate functional elements in genomic …

Our growing awareness of the microbial world’s importance and diversity contrasts starkly
with our limited understanding of its fundamental structure. Despite recent advances in DNA …

In the favoured core-accretion model of formation of planetary systems, solid planetesimals
accumulate to build up planetary cores, which then accrete nebular gas if they are sufficiently …

The comparison of related genomes has emerged as a powerful lens for genome interpretation.
Here we report the sequencing and comparative analysis of 29 eutherian genomes. We …

The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an
ongoing global pandemic due in part to the challenge of identifying symptomatic, asymptomatic, …

Comprehensive, high-quality reference genomes are required for functional characterization
and taxonomic assignment of the human gut microbiota. We present the Unified Human …

The developmental and evolutionary mechanisms behind the emergence of human-specific
brain features remain largely unknown. However, the recent ability to compare our genome …