User profiles for K. Pogliano

Kit Pogliano

Professor, Biological Sciences, UC San Diego
Verified email at ucsd.edu
Cited by 13379

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

…, R Knight, PR Jensen, BŲ Palsson, K Pogliano… - Nature …, 2016 - nature.com
The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

Microbial metabolic exchange—the chemotype-to-phenotype link

VV Phelan, WT Liu, K Pogliano… - Nature chemical …, 2012 - nature.com
The function of microbial interactions is to enable microorganisms to survive by establishing
a homeostasis between microbial neighbors and local environments. A microorganism can …

Primer on agar-based microbial imaging mass spectrometry

…, BS Moore, SS Golden, K Pogliano… - Journal of …, 2012 - Am Soc Microbiol
Matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) imaging mass spectrometry
(IMS) applied directly to microbes on agar-based medium captures global information …

Mass spectral molecular networking of living microbial colonies

…, M van der Voort, K Pogliano… - Proceedings of the …, 2012 - National Acad Sciences
… to connect to its top K scoring matches (we typically allow a maximum of 10 connections
per node). Edges between spectra are retained only if in the top K for both paired spectra and …

Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules

…, M Burkart, K Pogliano, J Pogliano - Proceedings of the …, 2013 - National Acad Sciences
Identifying the mechanism of action for antibacterial compounds is essential for understanding
how bacteria interact with one another and with other cell types and for antibiotic …

[PDF][PDF] c-Jun is essential for organization of the epidermal leading edge

…, SK Hanks, K Nason, JM Arbeit, K Pogliano… - Developmental cell, 2003 - cell.com
The migration of epithelial layers requires specific and coordinated organization of the cells
at the leading edge of the sheet. Mice that are conditionally deleted for the c-jun …

MS/MS networking guided analysis of molecule and gene cluster families

…, N Bandeira, BŲ Palsson, K Pogliano… - Proceedings of the …, 2013 - National Acad Sciences
The ability to correlate the production of specialized metabolites to the genetic capacity of
the organism that produces such molecules has become an invaluable tool in aiding the …

Assembly of a nucleus-like structure during viral replication in bacteria

…, K Pogliano, E Villa, DA Agard, J Pogliano - Science, 2017 - science.org
We observed the assembly of a nucleus-like structure in bacteria during viral infection. Using
fluorescence microscopy and cryo-electron tomography, we showed that Pseudomonas …

A vital stain for studying membrane dynamics in bacteria: a novel mechanism controlling septation during Bacillus subtilis sporulation

…, A Perez, YL Sun, K Pogliano - Molecular …, 1999 - Wiley Online Library
At the onset of sporulation in Bacillus subtilis, two potential division sites are assembled at
each pole, one of which will be used to synthesize the asymmetrically positioned sporulation …

Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites

J Pogliano, K Pogliano, DS Weiss… - Proceedings of the …, 1997 - National Acad Sciences
k–m, showing the inferred outlines of the cells (black), and the positions of the nucleoids (red),
and the FtsZ rings (green). (o–q) A different field of cells from the same experiment as in k–…