The steady expansion in the capacity of modern beamlines for high-throughput data collection,
enabled by increasing X-ray brightness, capacity of robotics and detector speeds, has …

Inorganic arsenic (iAs) in 13 store-bought edible seaweed samples and 34 dried kelp (Laminaria
digitata) samples was determined by a newly developed, field-deployable method (…

Hit finding in early drug discovery is often based on high throughput screening (HTS) of
existing and historical compound libraries, which can limit chemical diversity, is time-consuming, …

Macromolecular crystallography (MX) has been a motor for biology for over half a century
and this continues apace. A series of revolutions, including the production of recombinant …

… Under these conditions, we were able to calculate the values of K 0.5 3.9 ± 0.5 μM for
NendoU hex , and K m of 7.4 ± 1.0 μM for NendoU mon , indicating that the hexamer form has an …

It is advisable to monitor and regulate inorganic arsenic (iAs) in food and feedstuff. This work
describes an update and validation of a method of selective hydride generation (HG) with …

… The results showed that fragment binding could be detected over a K D range of 10–1000
μM, with good correlation between apparent K D of compounds calculated by WAC with IC 50 …

The ongoing explosion in genomics data has long since outpaced the capacity of conventional
biochemical methodology to verify the large number of hypotheses that emerge from the …

The CCP4 (Collaborative Computational Project, Number 4) software suite for macromolecular
structure determination by X-ray crystallography groups brings together many programs …

Brown seaweed such as Laminaria digitata is known to accumulate arsenic at a concentration
of more than 100 mg kg−1. How the algae can tolerate such a high level of arsenic has …