User profiles for K. Nakai
Kenta Nakaithe Institute of Medical Science, the University of Tokyo Verified email at ims.u-tokyo.ac.jp Cited by 27911 |
PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization
… The k-nearest-neighbor method is a pattern-recognition algorithm in which k is a pre-defined …
Then, the candidate site that occupies the majority of the k-nearest sequences is assigned …
Then, the candidate site that occupies the majority of the k-nearest sequences is assigned …
[HTML][HTML] What are reactive oxygen species, free radicals, and oxidative stress in skin diseases?
K Nakai, D Tsuruta - International journal of molecular sciences, 2021 - mdpi.com
Oxygen in the atmosphere is a crucial component for life-sustaining aerobic respiration in
humans. Approximately 95% of oxygen is consumed as energy and ultimately becomes water; …
humans. Approximately 95% of oxygen is consumed as energy and ultimately becomes water; …
Protein sorting signals and prediction of subcellular localization
K Nakai - Advances in protein chemistry, 2000 - Elsevier
Recent advances in large-scale sequencing has accelerated the identification of potential
genes. To find the function of these genes, the homology search technique has been routinely …
genes. To find the function of these genes, the homology search technique has been routinely …
WoLF PSORT: protein localization predictor
…, H Harada, CJ Adams-Collier, K Nakai - Nucleic acids …, 2007 - academic.oup.com
… After conversion, a simple k-nearest neighbor classifier is used for prediction. Using html,
the evidence for each prediction is shown in two ways: (i) a list of proteins of known localization …
the evidence for each prediction is shown in two ways: (i) a list of proteins of known localization …
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
…, T Tsujimura, DM Standley, K Nakanishi, K Nakai… - Nature …, 2010 - nature.com
Polarization of macrophages to M1 or M2 cells is important for mounting responses against
bacterial and helminth infections, respectively. Jumonji domain containing-3 (Jmjd3), a …
bacterial and helminth infections, respectively. Jumonji domain containing-3 (Jmjd3), a …
A knowledge base for predicting protein localization sites in eukaryotic cells
K Nakai, M Kanehisa - Genomics, 1992 - Elsevier
… amino acids (K or R) or of three basic amino acids (K or R) and … four-residue segment
containing three K or R residues (rule '… If the sum of K and R compositions is higher than 20%, then …
containing three K or R residues (rule '… If the sum of K and R compositions is higher than 20%, then …
[HTML][HTML] PrognoScan: a new database for meta-analysis of the prognostic value of genes
Background In cancer research, the association between a gene and clinical outcome
suggests the underlying etiology of the disease and consequently can motivate further studies. …
suggests the underlying etiology of the disease and consequently can motivate further studies. …
[PDF][PDF] T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development
…, J Huehn, HJ Fehling, T Sparwasser, K Nakai… - Immunity, 2012 - cell.com
The transcription factor Foxp3 is essential for the development of regulatory T (Treg) cells,
yet its expression is insufficient for establishing the Treg cell lineage. Here we showed that …
yet its expression is insufficient for establishing the Treg cell lineage. Here we showed that …
Expert system for predicting protein localization sites in gram‐negative bacteria
K Nakai, M Kanehisa - Proteins: Structure, Function, and …, 1991 - Wiley Online Library
… Most of the rules described in this work can also be used for eukaryotic proteins with minor
modifications (Nakai and Kanehisa, in preparation). In addition, by regarding the external …
modifications (Nakai and Kanehisa, in preparation). In addition, by regarding the external …
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes
…, T Tanase, K Nagai, H Kikuchi, K Nakai… - Genome …, 2006 - genome.cshlp.org
By analyzing 1,780,295 5′-end sequences of human full-length cDNAs derived from 164
kinds of oligo-cap cDNA libraries, we identified 269,774 independent positions of …
kinds of oligo-cap cDNA libraries, we identified 269,774 independent positions of …