User profiles for K. Macleod

Ken MacLeod

Professor of Geological Sciences, University of Missouri
Verified email at missouri.edu
Cited by 9570

[PDF][PDF] Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

…, KF Macleod, W Malorni, W Martinet, K Matsuoka… - Autophagy, 2008 - Taylor & Francis
Research in autophagy continues to accelerate, 1 and as a result many new scientists are
entering the field. Accordingly, it is important to establish a standard set of criteria for …

Autophagy: cellular and molecular mechanisms

D Glick, S Barth, KF Macleod - The Journal of pathology, 2010 - Wiley Online Library
Autophagy is a self‐degradative process that is important for balancing sources of energy at
critical times in development and in response to nutrient stress. Autophagy also plays a …

Autophagy in major human diseases

…, S Kumar, C Lopez‐Otin, KF Macleod… - The EMBO …, 2021 - embopress.org
Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity

…, J Herlitz, P Hildebrandt, K MacLeod… - European heart …, 2005 - academic.oup.com
Aims Patients with diabetes have an unfavourable prognosis after an acute myocardial
infarction. In the first DIGAMI study, an insulin-based glucose management improved survival. In …

The Chicxulub asteroid impact and mass extinction at the Cretaceous-Paleogene boundary

…, W Kiessling, C Koeberl, DA Kring, KG MacLeod… - science, 2010 - science.org
… Claims of gradual or stepwise extinctions during the Late Cretaceous culminating in the K-Pg
mass extinction (14) and survivorship through the K-Pg boundary may be explained by …

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.

KF Macleod, N Sherry, G Hannon, D Beach… - Genes & …, 1995 - genesdev.cshlp.org
Expression of p21 has been shown to be up-regulated by the p53 tumor suppressor gene in
vitro in response to DNA-damaging agents. However, p21 expression can be regulated …

Autophagy: assays and artifacts

S Barth, D Glick, KF Macleod - The Journal of pathology, 2010 - Wiley Online Library
… Additional aspects to successful blotting for LC3-I and -II include the use of PVDF membrane
as opposed to nitrocellulose and extraction in a detergent based buffer (Barth and Macleod, …

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

J Arthos, C Cicala, E Martinelli, K Macleod… - Nature …, 2008 - nature.com
Infection with human immunodeficiency virus 1 (HIV-1) results in the dissemination of virus
to gut-associated lymphoid tissue. Subsequently, HIV-1 mediates massive depletion of gut …

Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma

GW Chalmers, KJ Macleod, SA Little, LJ Thomson… - Thorax, 2002 - thorax.bmj.com
Background: Although inhaled corticosteroids have an established role in the treatment of
asthma, studies have tended to concentrate on non-smokers and little is known about the …

Frequency of severe hypoglycemia in patients with type I diabetes with impaired awareness of hypoglycemia

AE Gold, KM Macleod, BM Frier - Diabetes care, 1994 - Am Diabetes Assoc
K$a , Episodes of hypoglycemia occurring during sleep; WM, episodes occurring while …
MacLeod KM, Hepburn DA, Frier BM: Frequency and morbidity of severe hypoglycaemia in …