… the degree k of nodes in protein interaction networks against the probability of observing that
degree P(k), follows a power law (Bb). In these networks the clustering coefficient C(k) does …

We performed a systematic, large-scale analysis of human protein complexes comprising
gene products implicated in many different categories of human disease to create a phenome-…

Genetic risk for autism spectrum disorder (ASD) is associated with hundreds of genes
spanning a wide range of biological functions 1 , 2 , 3 , 4 , 5 – 6 . The alterations in the human …

Balanced chromosomal abnormalities (BCAs) represent a relatively untapped reservoir of
single-gene disruptions in neurodevelopmental disorders (NDDs). We sequenced BCAs in …

Genome-wide association (GWA) studies have identified numerous, replicable, genetic
associations between common single nucleotide polymorphisms (SNPs) and risk of common …

Genome-scale human protein–protein interaction networks are critical to understanding cell
biology and interpreting genomic data, but challenging to produce experimentally. Through …

Migraine is the most common brain disorder, affecting approximately 14% of the adult
population, but its molecular mechanisms are poorly understood. We report the results of a meta-…

Lysine acetylation is a major posttranslational modification involved in a broad array of
physiological functions. Here, we provide an organ-wide map of lysine acetylation sites from 16 …

… O’Reilly for help with SNV experimental validation, K. Yip for target-gene identification, and
Z… Looareesuwan S., Clark AG, Tokunaga K., Extended linkage disequilibrium surrounding the …

Genome-wide association studies (GWAS) have defined over 150 genomic regions
unequivocally containing variation predisposing to immune-mediated disease. Inferring disease …