User profiles for K. Kostarelos

Kostas Kostarelos

Nanomedicine Lab, ICREA & ICN2, Barcelona, Spain and University of Manchester, UK
Verified email at icn2.cat
Cited by 41388

Applications of carbon nanotubes in drug delivery

A Bianco, K Kostarelos, M Prato - Current opinion in chemical biology, 2005 - Elsevier
The development of new and efficient drug delivery systems is of fundamental importance to
improve the pharmacological profiles of many classes of therapeutic molecules. Many …

Functionalized carbon nanotubes in drug design and discovery

M Prato, K Kostarelos, A Bianco - Accounts of chemical research, 2008 - ACS Publications
Carbon nanotubes (CNTs) have been proposed and actively explored as multipurpose
innovative carriers for drug delivery and diagnostic applications. Their versatile physicochemical …

Promises, facts and challenges for carbon nanotubes in imaging and therapeutics

K Kostarelos, A Bianco, M Prato - Nature nanotechnology, 2009 - nature.com
The use of carbon nanotubes in medicine is now at the crossroads between a proof-of-principle
concept and an established preclinical candidate for a variety of therapeutic and …

Functionalized carbon nanotubes for plasmid DNA gene delivery

…, JP Briand, M Prato, K Kostarelos… - Angewandte Chemie …, 2004 - Wiley Online Library
5242 2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim DOI: 10.1002/anie. 200460437
Angew. Chem. Int. Ed. 2004, 43, 5242–5246 research.[1–11] In particular, the use of CNTs …

Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type

K Kostarelos, L Lacerda, G Pastorin, W Wu… - Nature …, 2007 - nature.com
The development of nanomaterials for biomedical and biotechnological applications is an
area of research that holds great promise and intense interest 1 , and carbon-based …

Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers

…, M Prato, A Bianco, K Kostarelos - Proceedings of the …, 2006 - National Acad Sciences
Carbon nanotubes (CNT) are intensively being developed for biomedical applications
including drug and gene delivery. Although all possible clinical applications will require …

Biomedical applications of functionalised carbon nanotubes

A Bianco, K Kostarelos, CD Partidos… - Chemical …, 2005 - pubs.rsc.org
The organic functionalisation of carbon nanotubes can improve substantially their solubility
and biocompatibility profile; as a consequence, their manipulation and integration into …

Carbon nanotubes as nanomedicines: from toxicology to pharmacology

L Lacerda, A Bianco, M Prato, K Kostarelos - Advanced drug delivery …, 2006 - Elsevier
Various biomedical applications of carbon nanotubes have been proposed in the last few
years leading to the emergence of a new field in diagnostics and therapeutics. Most of these …

Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors

…, M Prato, A Bianco, K Kostarelos - Journal of the …, 2005 - ACS Publications
Carbon nanotubes (CNTs) constitute a class of nanomaterials that possess characteristics
suitable for a variety of possible applications. Their compatibility with aqueous environments …

Liposomes: from a clinically established drug delivery system to a nanoparticle platform for theranostic nanomedicine

WT Al-Jamal, K Kostarelos - Accounts of chemical research, 2011 - ACS Publications
For decades, clinicians have used liposomes, self-assembled lipid vesicles, as nanoscale
systems to deliver encapsulated anthracycline molecules for cancer treatment. The more …