User profiles for K. Karlsgodt

Katherine Karlsgodt

University of California, Los Angeles
Verified email at psych.ucla.edu
Cited by 5809

Structural and functional brain abnormalities in schizophrenia

KH Karlsgodt, D Sun… - Current directions in …, 2010 - journals.sagepub.com
Schizophrenia is associated with changes in the structure and functioning of a number of key
brain systems, including prefrontal and medial temporal lobe regions involved in working …

[HTML][HTML] Examining the psychosis continuum

P DeRosse, KH Karlsgodt - Current behavioral neuroscience reports, 2015 - Springer
The notion that psychosis may exist on a continuum with normal experience has been
proposed in multiple forms throughout the history of psychiatry. However, in recent years, there …

Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia

KH Karlsgodt, D Sun, AM Jimenez… - Development and …, 2008 - cambridge.org
Schizophrenia has been thought of as a disorder of reduced functional and structural connectivity.
Recent advances in neuroimaging techniques such as functional magnetic resonance …

Diffusion tensor imaging of the superior longitudinal fasciculus and working memory in recent-onset schizophrenia

KH Karlsgodt, TGM van Erp, RA Poldrack… - Biological …, 2008 - Elsevier
BACKGROUND: Structural and functional abnormalities in frontal-parietal circuitry are thought
to be associated with working memory (WM) deficits in patients with schizophrenia. This …

[HTML][HTML] A phenome-wide examination of neural and cognitive function

…, E Congdon, W Triplett, KJ Gorgolewski, KH Karlsgodt… - Scientific data, 2016 - nature.com
This data descriptor outlines a shared neuroimaging dataset from the UCLA Consortium for
Neuropsychiatric Phenomics, which focused on understanding the dimensional structure of …

Antipsychotic treatment and functional connectivity of the striatum in first-episode schizophrenia

…, T Lencz, M Argyelan, T Ikuta, K Karlsgodt… - JAMA …, 2015 - jamanetwork.com
Importance Previous evidence has implicated corticostriatal abnormalities in the pathophysiology
of psychosis. Although the striatum is the primary target of all efficacious antipsychotics…

White matter integrity and prediction of social and role functioning in subjects at ultra-high risk for psychosis

KH Karlsgodt, TA Niendam, CE Bearden… - Biological psychiatry, 2009 - Elsevier
BACKGROUND: White matter microstructural disruptions have been observed in patients
with schizophrenia. However, whether changes exist prior to disease onset or in high-risk …

Dorsolateral prefrontal cortex activity during maintenance and manipulation of information in working memory in patients with schizophrenia

…, J Kim, TGM Van Erp, K Karlsgodt… - Archives of general …, 2005 - jamanetwork.com
K Does excessive memory load attenuate activation in the prefrontal cortex? load-dependent
processing in single and dual tasks: functional magnetic resonance imaging study. …

Baseline striatal functional connectivity as a predictor of response to antipsychotic drug treatment

…, PR Szeszko, KH Karlsgodt… - American Journal of …, 2016 - Am Psychiatric Assoc
Objective: Clinical response to antipsychotic drug treatment is highly variable, yet prognostic
biomarkers are lacking. The authors recently demonstrated that successful antipsychotic …

The role of myelination in measures of white matter integrity: combination of diffusion tensor imaging and two-photon microscopy of CLARITY intact brains

…, M Argyelan, M Aggarwal, TSS Chandon, KH Karlsgodt… - Neuroimage, 2017 - Elsevier
Diffusion tensor imaging (DTI) is used extensively in neuroscience to noninvasively estimate
white matter (WM) microarchitecture. However, the diffusion signal is inherently ambiguous …