The functions of pentraxins, like C-reactive protein (CRP), serum amyloid protein P (SAP)
and pentraxin-3 (PTX3), are to coordinate spatially and temporally targeted clearance of …

Complement factor H (FH) is an important regulator of the alternative complement pathway.
The Y402H polymorphism within the seventh short consensus repeat of FH was recently …

Complement-mediated inflammation or dysregulation in lipid metabolism are associated with
the pathogenesis of several diseases. These include age-related macular degeneration (…

Streptococci are a broad group of Gram‐positive bacteria. This genus includes various human
pathogens causing significant morbidity and mortality. Two of the most important human …

We report an unusual case of human babesiosis in Finland in a 53-year-old man with no
history of splenectomy. He had a rudimentary spleen, coexisting Lyme borreliosis, exceptional …

The APOE4 variant of apolipoprotein E (apoE) is the most prevalent genetic risk allele
associated with late‐onset Alzheimer's disease (AD). ApoE interacts with complement regulator …

The alternative pathway (AP) of complement is constantly active in plasma and can easily
be activated on self surfaces and trigger local inflammation. Host cells are protected from AP …

Aims The aim of the study was to investigate the inactivation by dentine of the antibacterial
activity of various commonly used local root canal medicaments. Methodology The …

Background Babesiosis is a globally growing tick-borne disease in humans. Severe
babesiosis caused by Babesia divergens has been reported in two patients from Asturias (…

The main virulence factor of group A streptococcus (GAS), M protein, binds plasma
complement regulators factor H (FH) and FH‐like protein 1 (FHL‐1) leading to decreased …