Soft matter models of developing tissues and tumors
D Gonzalez-Rodriguez, K Guevorkian, S Douezan… - Science, 2012 - science.org
… In the method proposed by Guevorkian et al. (21), an aggregate is aspirated at constant
suction pressure into a micropipette of smaller diameter than that of the aggregate, and the …
suction pressure into a micropipette of smaller diameter than that of the aggregate, and the …
Aspiration of biological viscoelastic drops
K Guevorkian, MJ Colbert, M Durth, S Dufour… - Physical review …, 2010 - APS
Spherical cellular aggregates are in vitro systems to study the physical and biophysical
properties of tissues. We present a novel approach to characterize the mechanical properties of …
properties of tissues. We present a novel approach to characterize the mechanical properties of …
Spreading dynamics and wetting transition of cellular aggregates
S Douezan, K Guevorkian, R Naouar… - Proceedings of the …, 2011 - National Acad Sciences
We study the spreading of spheroidal aggregates of cells, expressing a tunable level of E-cadherin
molecules, on glass substrates decorated with mixed fibronectin and polyethylene …
molecules, on glass substrates decorated with mixed fibronectin and polyethylene …
[PDF][PDF] A gradient of glycolytic activity coordinates FGF and Wnt signaling during elongation of the body axis in amniote embryos
… (K and L) Enzymatic detection of relative lactate level (K) and relative ATP concentration (L)
in the posterior region of control 2-day-old chicken embryos and in embryos cultured in …
in the posterior region of control 2-day-old chicken embryos and in embryos cultured in …
Mechanosensitive shivering of model tissues under controlled aspiration
K Guevorkian, D Gonzalez-Rodriguez… - Proceedings of the …, 2011 - National Acad Sciences
… By analogy with a viscoelastic liquid, we characterize the aggregate’s mechanical behavior
using a modified Maxwell model consisting of two springs of constants k 1 and k 2 and two …
using a modified Maxwell model consisting of two springs of constants k 1 and k 2 and two …
Micropipette aspiration: A unique tool for exploring cell and tissue mechanics in vivo
K Guevorkian, JL Maître - Methods in cell biology, 2017 - Elsevier
Cell and tissue mechanical properties are paramount in controlling morphogenesis.
Microaspiration techniques allow measuring the absolute values of mechanical properties in space …
Microaspiration techniques allow measuring the absolute values of mechanical properties in space …
[PDF][PDF] Spreading dynamics of biomimetic actin cortices
Reconstituted systems mimicking cells are interesting tools for understanding the details of
cell behavior. Here, we use an experimental system that mimics cellular actin cortices, …
cell behavior. Here, we use an experimental system that mimics cellular actin cortices, …
[PDF][PDF] Mechanics of biomimetic liposomes encapsulating an actin shell
… 3 C, where k is obtained from each Lcross separately. We have also observed that the
elastic coefficient k does not … We first analyze k values for bulk liposomes. The distribution of …
elastic coefficient k does not … We first analyze k values for bulk liposomes. The distribution of …
Swimming Paramecium in magnetically simulated enhanced, reduced, and inverted gravity environments
K Guevorkian, JM Valles Jr - Proceedings of the National …, 2006 - National Acad Sciences
Earth's gravity exerts relatively weak forces in the range of 10–100 pN directly on cells in
biological systems. Nevertheless, it biases the orientation of swimming unicellular organisms, …
biological systems. Nevertheless, it biases the orientation of swimming unicellular organisms, …
Rectified random cell motility as a mechanism for embryo elongation
The body of vertebrate embryos forms by posterior elongation from a terminal growth zone
called the tail bud. The tail bud is a source of highly motile cells that eventually constitute the …
called the tail bud. The tail bud is a source of highly motile cells that eventually constitute the …