The nasopharynx (NP) is a reservoir for microbes associated with acute respiratory
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …

Background Short-term targeted treatment can potentially prevent fall asthma exacerbations
while limiting therapy exposure. Objective We sought to compare (1) omalizumab with …

Background Human rhinoviruses (HRVs) are the most prevalent human pathogens, and consist
of 101 serotypes that are classified into groups A and B according to sequence variations…

To test the hypothesis that rhinovirus (RV)-induced immune responses influence the outcome
of RV infections, we inoculated 22 subjects with allergic rhinitis or asthma with RV16. …

Rationale: Allergic inflammation has been linked to increased susceptibility to viral illnesses,
but it is unclear whether this association is causal. Objectives: To test whether omalizumab …

Human respiratory viruses are a diverse group of pathogens composed of hundreds of virus
strains, and this presents a major challenge for diagnostic laboratories. To efficiently detect …

Repeated cycles of infection-associated lower airway inflammation drive the pathogenesis
of persistent wheezing disease in children. In this study, the occurrence of acute respiratory …

Importance In the United States, Black and Hispanic children have higher rates of asthma
and asthma-related morbidity compared with White children and disproportionately reside in …

We describe a lethal respiratory outbreak among wild chimpanzees in Uganda in 2013 for
which molecular and epidemiologic analyses implicate human rhinovirus C as the cause. …

Respiratory viruses of human origin infect wild apes across Africa, sometimes lethally. Here
we report simultaneous outbreaks of two distinct human respiratory viruses, human …