We developed a functional lineage tracing tool termed CaTCH (CRISPRa tracing of clones
in heterogeneous cell populations). CaTCH combines precise clonal tracing of millions of …

Background Amyloidoses are a group of usually fatal diseases, probably caused by protein
misfolding and subsequent aggregation into amyloid fibrillar deposits. The mechanisms …

The study of DNA sequence variation has been transformed by recent advances in DNA
sequencing technologies. Determination of the functional consequences of sequence variant …

… Instead, these tools combine a pseudo-mapping of the k-mers present within each read to
the k-mer distributions from the transcriptome annotation with an expectation maximization …

Adaptation of the functional proteome is essential to counter pathogens during infection, yet
precisely timed degradation of these response proteins after pathogen clearance is likewise …

Tristetraprolin (TTP) is a critical negative immune regulator. It binds AU-rich elements in the
untranslated-regions of many mRNAs encoding pro-inflammatory mediators, thereby …

Antisense transcription is known to have a range of impacts on sense gene expression,
including (but not limited to) impeding transcription initiation, disrupting post-transcriptional …

… be at least m − k letters belonging to the pattern [21]. In our case, by requiring ν − k of the
fragments (instead of all of them) to be perfectly matched on t, the non-candidates can be …

… Kimon Froussios … The authors wish it to be known that, in their opinion, Kimon Froussios
and Nick J. … The authors wish it to be known that, in their opinion, Kimon Froussios and Nick J. …

… Instead, these tools combine a pseudo-mapping of the k-mers present within each read
to the k-mer distributions from the transcript annotation with an expectation maximization …