User profiles for K. Forslund

Sofia K. Forslund

Junior Group Leader, ECRC (joint Max Delbrück Center and Charité University Hospital unit …
Verified email at embl.de
Cited by 56898

STRING v10: protein–protein interaction networks, integrated over the tree of life

…, A Franceschini, S Wyder, K Forslund… - Nucleic acids …, 2015 - academic.oup.com
The many functional partnerships and interactions that occur between proteins are at the
core of cellular processing and their systematic characterization helps to provide context in …

Human gut microbes impact host serum metabolome and insulin sensitivity

…, T Hyotylainen, T Nielsen, BAH Jensen, K Forslund… - Nature, 2016 - nature.com
Insulin resistance is a forerunner state of ischaemic cardiovascular disease and type 2
diabetes. Here we show how the human gut microbiome impacts the serum metabolome and …

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

K Forslund, F Hildebrand, T Nielsen, G Falony… - Nature, 2015 - nature.com
In recent years, several associations between common chronic human disorders and altered
gut microbiome composition and function have been reported 1 , 2 . In most of these reports…

The Pfam protein families database

…, J Tate, C Boursnell, N Pang, K Forslund… - Nucleic acids …, 2012 - academic.oup.com
Pfam is a widely used database of protein families, currently containing more than 13 000
manually curated protein families as of release 26.0. Pfam is available via servers in the UK ( …

The Pfam protein families database

…, P Gunasekaran, G Ceric, K Forslund… - Nucleic acids …, 2010 - academic.oup.com
Pfam is a widely used database of protein families and domains. This article describes a set
of major updates that we have implemented in the latest release (version 24.0). The most …

The Pfam protein families database

…, SJ Sammut, HR Hotz, G Ceric, K Forslund… - Nucleic acids …, 2007 - academic.oup.com
Pfam is a comprehensive collection of protein domains and families, represented as multiple
sequence alignments and as profile hidden Markov models. The current release of Pfam (…

Fast genome-wide functional annotation through orthology assignment by eggNOG-mapper

J Huerta-Cepas, K Forslund, LP Coelho… - Molecular biology …, 2017 - academic.oup.com
Orthology assignment is ideally suited for functional inference. However, because predicting
orthology is computationally intensive at large scale, and most pipelines are relatively …

eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences

J Huerta-Cepas, D Szklarczyk, K Forslund… - Nucleic acids …, 2016 - academic.oup.com
eggNOG is a public resource that provides Orthologous Groups (OGs) of proteins at
different taxonomic levels, each with integrated and summarized functional annotations. …

Salt-responsive gut commensal modulates TH17 axis and disease

…, MG Matus, SM Kearney, SW Olesen, K Forslund… - Nature, 2017 - nature.com
… The protocol was modified from the manufacturer’s instructions to include proteinase K
treatment to further lyse the cells. After addition of proteinase K (final concentration 5 mg ml −1 ) …

[HTML][HTML] Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

…, A Salonen, LJ Virta, RA Kekkonen, K Forslund… - Nature …, 2016 - nature.com
Early-life antibiotic use is associated with increased risk for metabolic and immunological
diseases, and mouse studies indicate a causal role of the disrupted microbiome. However, …