[PDF][PDF] Integrated genomic characterization of papillary thyroid carcinoma
…, GL Clayman, L Cope, JA Copland, K Covington… - Cell, 2014 - cell.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
[PDF][PDF] Comprehensive and integrative genomic characterization of hepatocellular carcinoma
…, R Bowlby, K Mungall, S Sadeghi, L Xi, K Covington… - Cell, 2017 - cell.com
Liver cancer has the second highest worldwide cancer mortality rate and has limited
therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole-exome …
therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole-exome …
[HTML][HTML] The repertoire of mutational signatures in human cancer
Somatic mutations in cancer genomes are caused by multiple mutational processes, each
of which generates a characteristic mutational signature 1 . Here, as part of the Pan-Cancer …
of which generates a characteristic mutational signature 1 . Here, as part of the Pan-Cancer …
[HTML][HTML] The prevalence and effect of burnout on graduate healthcare students
…, J Wimsatt, L Ledbetter, K Covington… - Canadian medical …, 2017 - ncbi.nlm.nih.gov
Burnout is a growing epidemic among professional healthcare students. Unaddressed burnout
has been shown to have psychological and performance related detriments. The purpose …
has been shown to have psychological and performance related detriments. The purpose …
Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer
…, A Tsimelzon, GM Poage, KR Covington… - Clinical Cancer …, 2015 - AACR
Purpose: Genomic profiling studies suggest that triple-negative breast cancer (TNBC) is a
heterogeneous disease. In this study, we sought to define TNBC subtypes and identify subtype…
heterogeneous disease. In this study, we sought to define TNBC subtypes and identify subtype…
Trans-ancestry mutational landscape of hepatocellular carcinoma genomes
Y Totoki, K Tatsuno, KR Covington, H Ueda… - Nature …, 2014 - nature.com
Diverse epidemiological factors are associated with hepatocellular carcinoma (HCC) prevalence
in different populations. However, the global landscape of the genetic changes in HCC …
in different populations. However, the global landscape of the genetic changes in HCC …
[PDF][PDF] Comprehensive pan-genomic characterization of adrenocortical carcinoma
…, M Sibony, Z Sanborn, M Bellair, C Buhay, K Covington… - Cancer cell, 2016 - cell.com
We describe a comprehensive genomic characterization of adrenocortical carcinoma (ACC).
Using this dataset, we expand the catalogue of known ACC driver genes to include …
Using this dataset, we expand the catalogue of known ACC driver genes to include …
[HTML][HTML] Scalable open science approach for mutation calling of tumor exomes using multiple genomic pipelines
The Cancer Genome Atlas (TCGA) cancer genomics dataset includes over 10,000 tumor-normal
exome pairs across 33 different cancer types, in total >400 TB of raw data files requiring …
exome pairs across 33 different cancer types, in total >400 TB of raw data files requiring …
[PDF][PDF] Integrative genomic analysis of cholangiocarcinoma identifies distinct IDH-mutant molecular profiles
Cholangiocarcinoma (CCA) is an aggressive malignancy of the bile ducts, with poor
prognosis and limited treatment options. Here, we describe the integrated analysis of somatic …
prognosis and limited treatment options. Here, we describe the integrated analysis of somatic …
Mutational landscape of aggressive cutaneous squamous cell carcinoma
…, H Doddapaneni, E Shinbrot, KR Covington… - Clinical cancer …, 2014 - AACR
Purpose: Aggressive cutaneous squamous cell carcinoma (cSCC) is often a disfiguring and
lethal disease. Very little is currently known about the mutations that drive aggressive cSCC. …
lethal disease. Very little is currently known about the mutations that drive aggressive cSCC. …