Secondary metabolites produced by bacteria and fungi are an important source of
antimicrobials and other bioactive compounds. In recent years, genome mining has seen broad …

Many drugs are derived from small molecules produced by microorganisms and plants, so-called
natural products. Natural products have diverse chemical structures, but the …

Many microorganisms produce natural products that form the basis of antimicrobials,
antivirals, and other drugs. Genome mining is routinely used to complement screening-based …

Microorganisms produce small bioactive compounds as part of their secondary or specialised
metabolism. Often, such metabolites have antimicrobial, anticancer, antifungal, antiviral or …

A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi
and plants are known to be encoded in biosynthetic gene clusters. Information about these …

Microbial secondary metabolism constitutes a rich source of antibiotics, chemotherapeutics,
insecticides and other high-value chemicals. Genome mining of gene clusters that encode …

Bacterial and fungal secondary metabolism is a rich source of novel bioactive compounds
with potential pharmaceutical applications as antibiotics, anti-tumor drugs or cholesterol-…

Many antibiotics, chemotherapeutics, crop protection agents and food preservatives originate
from molecules produced by bacteria, fungi or plants. In recent years, genome mining …

With an ever-increasing amount of (meta)genomic data being deposited in sequence databases,
(meta)genome mining for natural product biosynthetic pathways occupies a critical role …

Developments in computational omics technologies have provided new means to access the
hidden diversity of natural products, unearthing new potential for drug discovery. In parallel…