Translocation of surface-localized effectors in type III secretion

K Akopyan, T Edgren… - Proceedings of the …, 2011 - National Acad Sciences
… proteinase K protection experiments. In logarithmically growing bacteria, 50 to 70% of YopE,
YopH, YopB, and YopD, but not YerA (SycE), was accessible to proteinase K degradation, …

[PDF][PDF] DNA replication determines timing of mitosis by restricting CDK1 and PLK1 activation

B Lemmens, N Hegarat, K Akopyan, J Sala-Gaston… - Molecular cell, 2018 - cell.com
To maintain genome stability, cells need to replicate their DNA before dividing. Upon
completion of bulk DNA synthesis, the mitotic kinases CDK1 and PLK1 become active and drive …

[PDF][PDF] Neutralization of the positive charges on histone tails by RNA promotes an open chromatin structure

R Dueva, K Akopyan, C Pederiva, D Trevisan… - Cell Chemical …, 2019 - cell.com
… The fact that histone tails are enriched in positively charged lysine (K) and arginine (R) (in
the case of H2B, 43% K/R in the tail [15/35] versus 14% K/R in the histone fold domain [13/91]) …

Biomodification of meat for improving functional-technological properties of minced meat

…, A Koshchaev, N Kenijz, K Akopyan… - Research Journal of …, 2018 - elibrary.ru
Biomodification Of Meat For Improving Functional-Technological Properties Of Minced Meat
КОРЗИНА ПОИСК НАВИГАТОР ЖУРНАЛЫ КНИГИ ПАТЕНТЫ ПОИСК АВТОРЫ …

[PDF][PDF] Assessing kinetics from fixed cells reveals activation of the mitotic entry network at the S/G2 transition

K Akopyan, HS Cascales, E Hukasova, AT Saurin… - Molecular cell, 2014 - cell.com
During the cell cycle, DNA duplication in S phase must occur before a cell divides in mitosis.
In the intervening G2 phase, mitotic inducers accumulate, which eventually leads to a switch…

Assessment of residential soil contamination with arsenic and lead in mining and smelting towns of northern Armenia

K Akopyan, V Petrosyan, R Grigoryan… - Journal of Geochemical …, 2018 - Elsevier
Environmental characterization was conducted in one mining and one smelting community in
Armenia, Akhtala and Alaverdi, respectively. The aim of the study was to quantify the levels …

Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers

…, D Lindenhofer, Y Wang, K Akopyan… - Nucleic acids …, 2020 - academic.oup.com
Ligand binding induces extensive spatial reorganization and clustering of the EphA2 receptor
at the cell membrane. It has previously been shown that the nanoscale spatial distribution …

ATM/Wip1 activities at chromatin control Plk1 re‐activation to determine G2 checkpoint duration

…, J Benada, E Müllers, K Akopyan, K Burdova… - The EMBO …, 2017 - embopress.org
After DNA damage, the cell cycle is arrested to avoid propagation of mutations. Arrest in G2
phase is initiated by ATM ‐/ ATR ‐dependent signaling that inhibits mitosis‐promoting …

[HTML][HTML] Effectiveness and safety of a shorter treatment regimen in a setting with a high burden of multidrug-resistant tuberculosis

A Trubnikov, A Hovhannesyan, K Akopyan… - International Journal of …, 2021 - mdpi.com
Treatment of drug-resistant tuberculosis is lengthy, insufficiently effective, and toxic. Since
2016, the World Health Organization has recommended shorter treatment regimens (STR). We …

[HTML][HTML] Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism

A Waraky, K Akopyan, V Parrow, T Strömberg… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Akopyan and Mr. Waraky declare no potential conflict of interest. Dr. … Menu E, Jernberg-Wiklund
H, Stromberg T, De Raeve H, Girnita L, Larsson O, Axelson M, Asosingh K, Nilsson K, Van …