User profiles for K. Y. Orostica

Karen Oróstica

Instituto de Investigación Interdisciplinaria, Vicerrectoría Académica, Universidad de Talca …
Verified email at utalca.cl
Cited by 86

New year, new SARS-CoV-2 variant: Resolutions on genomic surveillance protocols to face Omicron

KY Oróstica, S Contreras, A Sanchez-Daza… - The Lancet Regional …, 2022 - thelancet.com
The emergence of SARS-CoV-2 variants with enhanced transmissibility and partial immune
escape (also known as Variants of Concern, VOC) has characterised the second year of the …

chromPlot: visualization of genomic data in chromosomal context

KY Oróstica, RA Verdugo - Bioinformatics, 2016 - academic.oup.com
Visualizing genomic data in chromosomal context can help detecting errors in data processing
and may suggest new hypotheses to be tested. Here, we report a new tool for displaying …

Mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants

KY Oróstica, S Contreras, SB Mohr, J Dehning… - arXiv preprint arXiv …, 2021 - arxiv.org
The emergence of SARS-CoV-2 variants of concern endangers the long-term control of
COVID-19, especially in countries with limited genomic surveillance. In this work, we explored …

[HTML][HTML] Total mutational load and clinical features as predictors of the metastatic status in lung adenocarcinoma and squamous cell carcinoma patients

KY Oróstica, J Saez-Hidalgo, PR de Santiago… - Journal of Translational …, 2022 - Springer
Background Recently, extensive cancer genomic studies have revealed mutational and clinical
data of large cohorts of cancer patients. For example, the Pan-Lung Cancer 2016 dataset …

Model-based assessment of sampling protocols for infectious disease genomic surveillance

S Contreras, KY Oróstica, A Daza-Sanchez… - Chaos, Solitons & …, 2023 - Elsevier
Genomic surveillance of infectious diseases allows monitoring circulating and emerging
variants and quantifying their epidemic potential. However, due to the high costs associated …

BEST: a Shiny/R web-based application to easily retrieve cross-related enzyme functional parameters and information from BRENDA

JS Hidalgo, KY Oróstica, A Sanchez–Daza… - …, 2021 - academic.oup.com
… Karen Y Oróstica , Karen Y Oróstica … Juan Saez Hidalgo, Karen Y Oróstica, Anamaria
Sanchez–Daza, Álvaro Olivera–Nappa, BEST: a Shiny/R web-based application to easily retrieve …

Visualization of Results from Systems Genetics Studies in Chromosomal Context

KY Oróstica, RA Verdugo - Systems Genetics: Methods and Protocols, 2017 - Springer
This chapter describes methods currently available for visualizing results from systems
genetics experiments. Here, we abstract from the statistical methods used for genetic mapping, …

Implementación de modelos de clasificación en cáncer basados en datos mutacionales y clínicos

KY Oróstica Tapia - 2021 - repositorio.uchile.cl
El cáncer es la segunda causa principal de muerte en el mundo, generando 9.6 millones
de decesos durante 2018. Ésta es una enfermedad compleja que combina tanto factores …

Mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants (preprint)

KY Oróstica, S Contreras, SB Mohr, J Dehning, S Bauer… - 2021 - pesquisa.bvsalud.org
The emergence of SARS-CoV-2 variants of concern endangers the long-term control of
COVID-19, especially in countries with limited genomic surveillance. In this work, we explored …

[CITATION][C] chromPlot: global visualization tool of genomic data

RA Verdugo, KY Orostica - R package version, 2019