Type IV pili: dynamics, biophysics and functional consequences
The surfaces of many bacteria are decorated with long, exquisitely thin appendages called
type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a …
type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a …
Bacterial phytochromes: more than meets the light
ME Auldridge, KT Forest - Critical reviews in biochemistry and …, 2011 - Taylor & Francis
Phytochromes are environmental sensors, historically thought of as red/far-red photoreceptors
in plants. Their photoperception occurs through a covalently linked tetrapyrrole …
in plants. Their photoperception occurs through a covalently linked tetrapyrrole …
A light-sensing knot revealed by the structure of the chromophore-binding domain of phytochrome
JR Wagner, JS Brunzelle, KT Forest, RD Vierstra - Nature, 2005 - nature.com
Phytochromes are red/far-red light photoreceptors that direct photosensory responses
across the bacterial, fungal and plant kingdoms. These include photosynthetic potential and …
across the bacterial, fungal and plant kingdoms. These include photosynthetic potential and …
Structure of the fibre-forming protein pilin at 2.6 Ć resolution
HE Parge, KT Forest, MJ Hickey, DA Christensen… - Nature, 1995 - nature.com
… Maximum colour saturation of blue and red corresponds to potentials of > |2 kT/e]. f Epitope
mapping, view as in d. Peptides that elicit antibodies blocking cell binding (blue, residues 41–…
mapping, view as in d. Peptides that elicit antibodies blocking cell binding (blue, residues 41–…
[HTML][HTML] Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin
…, SJ Lloyd, DS Shin, ED Getzoff, M Yeager, KT Forest… - Molecular cell, 2003 - cell.com
Pilin assembly into type IV pili is required for virulence by bacterial pathogens that cause
diseases such as cholera, pneumonia, gonorrhea, and meningitis. Crystal structures of soluble, …
diseases such as cholera, pneumonia, gonorrhea, and meningitis. Crystal structures of soluble, …
Structural insights into the Type II secretion nanomachine
LS McLaughlin, RJF Haft, KT Forest - Current opinion in structural biology, 2012 - Elsevier
… Work on the T4P and T2SS in the Forest lab is supported by the NIH (GM59271). RJFH was
funded by the DOE Great Lakes Bioenergy Research Center (DOE BER Office of Science DE…
funded by the DOE Great Lakes Bioenergy Research Center (DOE BER Office of Science DE…
[HTML][HTML] High resolution structure of Deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution
…, J Zhang, JS Brunzelle, RD Vierstra, KT Forest - Journal of biological …, 2007 - ASBMB
Phytochromes are red/far red light photochromic photoreceptors that direct many
photosensory behaviors in the bacterial, fungal, and plant kingdoms. They consist of an N-terminal …
photosensory behaviors in the bacterial, fungal, and plant kingdoms. They consist of an N-terminal …
Containerless vitrification of mammalian oocytes and embryos
M Lane, BD Bavister, EA Lyons, KT Forest - Nature biotechnology, 1999 - nature.com
… Forest … A US patent covering this technology has been applied for (Forest and Lane, #60/104,266). …
Forest …
Forest …
[HTML][HTML] Mutational analysis of Deinococcus radiodurans bacteriophytochrome reveals key amino acids necessary for the photochromicity and proton exchange cycle …
…, MA Mroginski, JM Walker, KT Forest… - Journal of Biological …, 2008 - ASBMB
The ability of phytochromes (Phy) to act as photointerconvertible light switches in plants and
microorganisms depends on key interactions between the bilin chromophore and the …
microorganisms depends on key interactions between the bilin chromophore and the …
Stereoelectronic and steric effects in side chains preorganize a protein main chain
…, KA Satyshur, KT Forest… - Proceedings of the …, 2010 - National Acad Sciences
Preorganization is shown to endow a protein with extraordinary conformational stability.
This preorganization is achieved by installing side-chain substituents that impose …
This preorganization is achieved by installing side-chain substituents that impose …