In the years of personalized (or precision) medicine the ‘omics’ methodologies in biomedical
sciences—genomics, transcriptomics, proteomics and metabolomics—are helping …

The POZ domain is a conserved protein–protein interaction motif present in a variety of
transcription factors involved in development, chromatin remodelling and human cancers. Here, …

Nuclear pore complexes (NPCs) are multisubunit protein entities embedded into the
nuclear envelope (NE). Here, we examine the in vivo dynamics of the essential Drosophila …

Enhancers have been defined as cis-acting DNA sequences that stimulate transcription
from a linked promoter in a distance-and orientation-independent manner. How enhancers …

Chromatin is a highly dynamic structure that plays a key role in the orchestration of gene
expression patterns during cellular differentiation and development. The packaging of DNA into …

Trithorax (TRX) is a Drosophila SET domain protein that is required for the correct expression
of homeotic genes. Here, we show that the TRX SET domain efficiently binds to core …

Hepatitis C virus is the major cause of chronic liver diseases and the only cytoplasmic RNA
virus known to be oncogenic in humans. The viral genome gives rise to ten mature proteins …

A set of arylazo sulfones, known to undergo N–S bond cleavage upon light exposure, has
been synthesized, and their activity in the dark and upon irradiation towards DNA has been …

There is growing evidence for the involvement of Y-complex nucleoporins (Y-Nups) in
cellular processes beyond the inner core of nuclear pores of eukaryotes. To comprehensively …

A number of p-pyridinyl oxime carbamate derivatives were prepared upon the reaction of the
corresponding oximes with isocyanates. These novel compounds reacted photochemically …