Defining functional DNA elements in the human genome
With the completion of the human genome sequence, attention turned to identifying and
annotating its functional DNA elements. As a complement to genetic and comparative genomics …
annotating its functional DNA elements. As a complement to genetic and comparative genomics …
Classification, epidemiology, and natural history of fibromyalgia
KP White, M Harth - Current pain and headache reports, 2001 - Springer
… , and Natural History of Fibromyalgia • White and Harth … Data from the 36-month assessment
are even more encouraging (White, … White KP, Harth M: The occurrence and impact of …
are even more encouraging (White, … White KP, Harth M: The occurrence and impact of …
The psychencode project
Recent research on disparate psychiatric disorders has implicated rare variants in genes
involved in global gene regulation and chromatin modification, as well as many common …
involved in global gene regulation and chromatin modification, as well as many common …
A Protein Interaction Map of Drosophila melanogaster
…, J Zhong, CA Stanyon, RL Finley Jr, KP White… - science, 2003 - science.org
Drosophila melanogaster is a proven model system for many aspects of human biology.
Here we present a two-hybrid–based protein-interaction map of the fly proteome. A total of …
Here we present a two-hybrid–based protein-interaction map of the fly proteome. A total of …
[HTML][HTML] Expanded encyclopaedias of DNA elements in the human and mouse genomes
…, J Zhang, SB Chhetri, J Zhang, A Victorsen, KP White… - Nature, 2020 - nature.com
… c, Percentages of regions that tested positive or negative for enhancer activity by MPRA in
lymphoblastoid cell lines (MPRA-positive, filled bars; MPRA-negative, white bars). The bars …
lymphoblastoid cell lines (MPRA-positive, filled bars; MPRA-negative, white bars). The bars …
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
…, MY Tolstorukov, KP White… - Genome …, 2012 - genome.cshlp.org
Chromatin immunoprecipitation (ChIP) followed by high-throughput DNA sequencing (ChIP-seq)
has become a valuable and widely used approach for mapping the genomic location of …
has become a valuable and widely used approach for mapping the genomic location of …
Gene Expression During the Life Cycle of Drosophila melanogaster
…, MA Krasnow, MP Scott, RW Davis, KP White - Science, 2002 - science.org
Molecular genetic studies of Drosophila melanogaster have led to profound advances in
understanding the regulation of development. Here we report gene expression patterns for …
understanding the regulation of development. Here we report gene expression patterns for …
Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE
To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
The predisposition to neuropsychiatric disease involves a complex, polygenic, and pleiotropic
genetic architecture. However, little is known about how genetic variants impart brain …
genetic architecture. However, little is known about how genetic variants impart brain …
[HTML][HTML] Unlocking the secrets of the genome
Despite the successes of genomics, little is known about how genetic information produces
complex organisms. A look at the crucial functional elements of fly and worm genomes could …
complex organisms. A look at the crucial functional elements of fly and worm genomes could …